Keith Romano

Hung Lab


Resident in Medicine


Email

Publications
    2013
  1. Ali A, Aydin C, Gildemeister R, Romano KP, Cao H, Ozen A, Soumana D, Newton A, Petropoulos CJ, Huang W, Schiffer CA. Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance. ACS Chem. Biol. 2013 Jul 19; 8(7):1469-78.

  2. 2012
  3. Romano KP, Ali A, Aydin C, Soumana D, Ozen A, Deveau LM, Silver C, Cao H, Newton A, Petropoulos CJ, Huang W, Schiffer CA. The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors. PLoS Pathog. 2012; 8(7):e1002832.

  4. 2011
  5. Romano KP, Laine JM, Deveau LM, Cao H, Massi F, Schiffer CA. Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease. J. Virol. 2011 Jul; 85(13):6106-16.

  6. 2010
  7. Romano KP, Ali A, Royer WE, Schiffer CA. Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proc. Natl. Acad. Sci. U.S.A. 2010 Dec 7; 107(49):20986-91.

  8. 2007
  9. Romano KP, Newman AG, Zahran RW, Millard JT. DNA interstrand cross-linking by epichlorohydrin. Chem. Res. Toxicol. 2007 May; 20(5):832-8.

  10. 2006
  11. Prabu-Jeyabalan M, Nalivaika EA, Romano K, Schiffer CA. Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate. J. Virol. 2006 Apr; 80(7):3607-16.

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