Life Sciences Building, KINSC S308
Haverford, PA 19041
About Justine Melo
Interests: Appetite regulation and behavioral responses to physiologic stress. I am interested in physiologic stress: the ways in which environment imposes stress on an organism, how stress is sensed at a cellular level, and the mechanisms by which stress signals are relayed to the nervous system to produce a highly adaptive dispersal behavior.Publications
- Melo JA, Ruvkun G. Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses. Cell 2012 Apr 13; 149(2):452-66.
- Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 2009 Feb 15; 23(4):496-511.
- Bonilla CY, Melo JA, Toczyski DP. Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol. Cell 2008 May 9; 30(3):267-76.
- Kaye JA, Melo JA, Cheung SK, Vaze MB, Haber JE, Toczyski DP. DNA breaks promote genomic instability by impeding proper chromosome segregation. Curr. Biol. 2004 Dec 14; 14(23):2096-106.