Andrej Savol

Sadreyev Lab

Bioinformatician Specialist


  1. Lau MS, Schwartz MG, Kundu S, Savol AJ, Wang PI, Marr SK, Grau DJ, Schorderet P, Sadreyev RI, Tabin CJ, Kingston RE. Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning. Science 2017 Mar 10; 355(6329):1081-1084.

  2. 2016
  3. Joh RI, Khanduja JS, Calvo IA, Mistry M, Palmieri CM, Savol AJ, Ho Sui SJ, Sadreyev RI, Aryee MJ, Motamedi M. Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs. Mol. Cell 2016 Dec 15; 64(6):1088-1101.

  4. 2015
  5. Savol AJ, Chennubhotla CS. Approximating frustration scores in complex networks via perturbed Laplacian spectra. Phys Rev E Stat Nonlin Soft Matter Phys 2015 Dec; 92(6-1):062806.

  6. 2014
  7. Savol AJ, Chennubhotla CS. Quantifying the Sources of Kinetic Frustration in Folding Simulations of Small Proteins. J Chem Theory Comput 2014 Aug 12; 10(8):2964-2974.

  8. Ramanathan A, Savol A, Burger V, Chennubhotla CS, Agarwal PK. Protein conformational populations and functionally relevant substates. Acc. Chem. Res. 2014 Jan 21; 47(1):149-56.

  9. 2013
  10. Taylor DP, Wells JZ, Savol A, Chennubhotla C. Modeling boundary conditions for balanced proliferation in metastatic latency. Clin. Cancer Res. 2013 Mar 1; 19(5):1063-70.

  11. 2012
  12. Ramanathan A, Savol AJ, Agarwal PK, Chennubhotla CS. Event detection and sub-state discovery from biomolecular simulations using higher-order statistics: application to enzyme adenylate kinase. Proteins 2012 Nov; 80(11):2536-51.

  13. Burger VM, Ramanathan A, Savol AJ, Stanley CB, Agarwal PK, Chennubhotla CS. Quasi-anharmonic analysis reveals intermediate states in the nuclear co-activator receptor binding domain ensemble. Pac Symp Biocomput 2012.

  14. 2011
  15. Savol AJ, Burger VM, Agarwal PK, Ramanathan A, Chennubhotla CS. QAARM: quasi-anharmonic autoregressive model reveals molecular recognition pathways in ubiquitin. Bioinformatics 2011 Jul 1; 27(13):i52-60.

  16. Ramanathan A, Savol AJ, Langmead CJ, Agarwal PK, Chennubhotla CS. Discovering conformational sub-states relevant to protein function. PLoS ONE 2011; 6(1):e15827.

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