Andrej Savol

Sadreyev Lab


Bioinformatician Specialist


Email

Publications
    2017
  1. Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, W├╝lfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M. Macrophages Facilitate Electrical Conduction in the Heart. Cell 2017 Apr 20; 169(3):510-522.e20.

  2. Choi J, Clement K, Huebner AJ, Webster J, Rose CM, Brumbaugh J, Walsh RM, Lee S, Savol A, Etchegaray JP, Gu H, Boyle P, Elling U, Mostoslavsky R, Sadreyev R, Park PJ, Gygi SP, Meissner A, Hochedlinger K. DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell 2017 Mar 29.

  3. Lau MS, Schwartz MG, Kundu S, Savol AJ, Wang PI, Marr SK, Grau DJ, Schorderet P, Sadreyev RI, Tabin CJ, Kingston RE. Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning. Science 2017 Mar 10; 355(6329):1081-1084.

  4. 2016
  5. Joh RI, Khanduja JS, Calvo IA, Mistry M, Palmieri CM, Savol AJ, Ho Sui SJ, Sadreyev RI, Aryee MJ, Motamedi M. Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs. Mol. Cell 2016 Dec 15; 64(6):1088-1101.

  6. 2015
  7. Savol AJ, Chennubhotla CS. Approximating frustration scores in complex networks via perturbed Laplacian spectra. Phys Rev E Stat Nonlin Soft Matter Phys 2015 Dec; 92(6-1):062806.

  8. 2014
  9. Savol AJ, Chennubhotla CS. Quantifying the Sources of Kinetic Frustration in Folding Simulations of Small Proteins. J Chem Theory Comput 2014 Aug 12; 10(8):2964-2974.

  10. Ramanathan A, Savol A, Burger V, Chennubhotla CS, Agarwal PK. Protein conformational populations and functionally relevant substates. Acc. Chem. Res. 2014 Jan 21; 47(1):149-56.

  11. 2013
  12. Taylor DP, Wells JZ, Savol A, Chennubhotla C. Modeling boundary conditions for balanced proliferation in metastatic latency. Clin. Cancer Res. 2013 Mar 1; 19(5):1063-70.

  13. 2012
  14. Ramanathan A, Savol AJ, Agarwal PK, Chennubhotla CS. Event detection and sub-state discovery from biomolecular simulations using higher-order statistics: application to enzyme adenylate kinase. Proteins 2012 Nov; 80(11):2536-51.

  15. Burger VM, Ramanathan A, Savol AJ, Stanley CB, Agarwal PK, Chennubhotla CS. Quasi-anharmonic analysis reveals intermediate states in the nuclear co-activator receptor binding domain ensemble. Pac Symp Biocomput 2012.

  16. 2011
  17. Savol AJ, Burger VM, Agarwal PK, Ramanathan A, Chennubhotla CS. QAARM: quasi-anharmonic autoregressive model reveals molecular recognition pathways in ubiquitin. Bioinformatics 2011 Jul 1; 27(13):i52-60.

  18. Ramanathan A, Savol AJ, Langmead CJ, Agarwal PK, Chennubhotla CS. Discovering conformational sub-states relevant to protein function. PLoS ONE 2011; 6(1):e15827.

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