Caroline Woo

Kingston Lab


Scientist at RANA Therapeutics

Department of Molecular Biology
Simches Research Center
Boston, MA 02114


Email

Website

About Caroline Woo

My research is focused upon understanding the mechanisms behind Polycomb-mediated repression of mammalian genes using a human embryonic stem cell model.

Publications
    2010
  1. Seong IS, Woda JM, Song JJ, Lloret A, Abeyrathne PD, Woo CJ, Gregory G, Lee JM, Wheeler VC, Walz T, Kingston RE, Gusella JF, Conlon RA, MacDonald ME. Huntingtin facilitates polycomb repressive complex 2. Hum. Mol. Genet. 2010 Feb 15; 19(4):573-83.

  2. Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. A region of the human HOXD cluster that confers polycomb-group responsiveness. Cell 2010 Jan 8; 140(1):99-110.

  3. 2008
  4. Kharchenko PV, Woo CJ, Tolstorukov MY, Kingston RE, Park PJ. Nucleosome positioning in human HOX gene clusters. Genome Res. 2008 Oct; 18(10):1554-61.

  5. 2007
  6. Woo CJ, Kingston RE. HOTAIR lifts noncoding RNAs to new levels. Cell 2007 Jun 29; 129(7):1257-9.

  7. 2004
  8. Bardwell PD, Woo CJ, Wei K, Li Z, Martin A, Sack SZ, Parris T, Edelmann W, Scharff MD. Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nat. Immunol. 2004 Feb; 5(2):224-9.

  9. Li Z, Woo CJ, Iglesias-Ussel MD, Ronai D, Scharff MD. The generation of antibody diversity through somatic hypermutation and class switch recombination. Genes Dev. 2004 Jan 1; 18(1):1-11.

  10. 2003
  11. Li Z, Woo CJ, Scharff MD. Mutations in AID and UNG extend the function of AID. Nat. Immunol. 2003 Oct; 4(10):945-6.

  12. Woo CJ, Martin A, Scharff MD. Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin. Immunity 2003 Oct; 19(4):479-89.

  13. 2002
  14. Martin A, Bardwell PD, Woo CJ, Fan M, Shulman MJ, Scharff MD. Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas. Nature 2002 Feb 14; 415(6873):802-6.

  15. 2001
  16. Zhang W, Bardwell PD, Woo CJ, Poltoratsky V, Scharff MD, Martin A. Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line. Int. Immunol. 2001 Sep; 13(9):1175-84.

  17. Poltoratsky V, Woo CJ, Tippin B, Martin A, Goodman MF, Scharff MD. Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation. Proc. Natl. Acad. Sci. U.S.A. 2001 Jul 3; 98(14):7976-81.

  18. 1999
  19. Vakkalanka RK, Woo C, Kirou KA, Koshy M, Berger D, Crow MK. Elevated levels and functional capacity of soluble CD40 ligand in systemic lupus erythematosus sera. Arthritis Rheum. 1999 May; 42(5):871-81.

  20. 1998
  21. Schattner EJ, Mascarenhas J, Reyfman I, Koshy M, Woo C, Friedman SM, Crow MK. Chronic lymphocytic leukemia B cells can express CD40 ligand and demonstrate T-cell type costimulatory capacity. Blood 1998 Apr 15; 91(8):2689-97.

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