Maria Alexander-Bridges

Avruch Lab


Consultant in Diabetes

Department of Molecular Biology
Simches Research Center
Boston, MA 02114


Email

About Maria Alexander-Bridges

My work focuses on developing compounds that modify insulin sensitivity.

Publications
    2010
  1. Nichols GA, Gandra SR, Chiou CF, Anthony MS, Alexander-Bridges M, Brown JB. Successes and challenges of insulin therapy for type 2 diabetes in a managed-care setting. Curr Med Res Opin 2010 Jan; 26(1):9-15.

  2. 2007
  3. Alexander-Bridges M, Doan LL, Endocrine Society's Task Force on Increasing Minority Participation in Clinical Research. Commentary on "increasing minority participation in clinical research": a white paper from the endocrine society. J. Clin. Endocrinol. Metab. 2007 Dec; 92(12):4557-9.

  4. 2001
  5. Cahill CM, Tzivion G, Nasrin N, Ogg S, Dore J, Ruvkun G, Alexander-Bridges M. Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways. J. Biol. Chem. 2001 Apr 20; 276(16):13402-10.

  6. 2000
  7. Nasrin N, Ogg S, Cahill CM, Biggs W, Nui S, Dore J, Calvo D, Shi Y, Ruvkun G, Alexander-Bridges MC. DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. Proc. Natl. Acad. Sci. U.S.A. 2000 Sep 12; 97(19):10412-7.

  8. 1998
  9. Buggs C, Nasrin N, Mode A, Tollet P, Zhao HF, Gustafsson JA, Alexander-Bridges M. IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBPalpha (CCAAT/enhancer-binding protein alpha)-stimulated expression of the sex-specific cytochrome P450 2C12 gene. Mol. Endocrinol. 1998 Sep; 12(9):1294-309.

  10. 1992
  11. Alexander-Bridges M, Mukhopadhyay NK, Jhala U, Denaro M, Kong XF, Avruch J, Maller J. Growth factor-activated kinases phosphorylate IRE-ABP. Biochem. Soc. Trans. 1992 Aug; 20(3):691-3.

  12. Alexander-Bridges M, Buggs C, Giere L, Denaro M, Kahn B, White M, Sukhatme V, Nasrin N. Models of insulin action on metabolic and growth response genes. Mol. Cell. Biochem. 1992 Feb 12; 109(2):99-105.

  13. Alexander-Bridges M, Ercolani L, Kong XF, Nasrin N. Identification of a core motif that is recognized by three members of the HMG class of transcriptional regulators: IRE-ABP, SRY, and TCF-1 alpha. J. Cell. Biochem. 1992 Feb; 48(2):129-35.

  14. Alexander-Bridges M, Dugast I, Ercolani L, Kong XF, Giere L, Nasrin N. Multiple insulin-responsive elements regulate transcription of the GAPDH gene. Adv. Enzyme Regul. 1992; 32:149-59.

  15. 1991
  16. Nasrin N, Buggs C, Kong XF, Carnazza J, Goebl M, Alexander-Bridges M. DNA-binding properties of the product of the testis-determining gene and a related protein. Nature 1991 Nov 28; 354(6351):317-20.

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