Department of Molecular Biology
Simches Research Center
Boston, MA 02114
About Behfar Ardehali
I received my B.Sc. in general biology from Shiraz University in Shiraz, Iran, and I obtained my Ph.D. in genetics from Cornell University in Ithaca, NY. I joined the Kingston Lab in the February of 2011 as a research fellow. Polycomb repressive complexes are required for proper development of multicellular organisms by facilitating silencing of a wide array of developmentally-regulated genes in a tightly-controlled spatial and temporal manner. I am interested in examining the mechanistic roles of polycomb repressive complexes in various biological processes.Publications
- Ardehali MB, Mei A, Zobeck KL, Caron M, Lis JT, Kusch T. Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription. EMBO J. 2011 Jul 20; 30(14):2817-28.
- Ardehali MB, Lis JT. Tracking rates of transcription and splicing in vivo. Nat. Struct. Mol. Biol. 2009 Nov; 16(11):1123-4.
- Fuda NJ, Ardehali MB, Lis JT. Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 2009 Sep 10; 461(7261):186-92.
- Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT. Spt6 enhances the elongation rate of RNA polymerase II in vivo. EMBO J. 2009 Apr 22; 28(8):1067-77.
- Yao J, Ardehali MB, Fecko CJ, Webb WW, Lis JT. Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation. Mol. Cell 2007 Dec 28; 28(6):978-90.
- Adelman K, Wei W, Ardehali MB, Werner J, Zhu B, Reinberg D, Lis JT. Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Mol. Cell. Biol. 2006 Jan; 26(1):250-60.