Aaron Engelhart

Szostak Lab


Research Fellow
Department of Molecular Biology
Simches Research Center
Boston, MA 02114


Email

About Aaron Engelhart

Self-assembly, nucleic acid polymerization

Publications
    2012
  1. Engelhart AE, Cafferty BJ, Okafor CD, Chen MC, Williams LD, Lynn DG, Hud NV. Nonenzymatic Ligation of DNA with a Reversible Step and a Final Linkage that Can Be Used in PCR. Chembiochem 2012 May 29; 13(8):1121-4.

    2. 2010
  2. Engelhart AE, Hud NV. Primitive genetic polymers. Cold Spring Harb Perspect Biol 2010 Dec; 2(12):a002196.

  3. Mamajanov I, Engelhart AE, Bean HD, Hud NV. DNA and RNA in anhydrous media: duplex, triplex, and G-quadruplex secondary structures in a deep eutectic solvent. Angew. Chem. Int. Ed. Engl. 2010 Aug 23; 49(36):6310-4.

  4. Horowitz ED, Engelhart AE, Chen MC, Quarles KA, Smith MW, Lynn DG, Hud NV. Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world. Proc. Natl. Acad. Sci. U.S.A. 2010 Mar 23; 107(12):5288-93.

    5. 2009
  5. Tsai AG, Engelhart AE, Hatmal MM, Houston SI, Hud NV, Haworth IS, Lieber MR. Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. J. Biol. Chem. 2009 Mar 13; 284(11):7157-64.

  6. Engelhart AE, Morton TH, Hud NV. Evidence of strong hydrogen bonding by 8-aminoguanine. Chem. Commun. (Camb.) 2009 Feb 14.

    7. 2008
  7. Cetinkol OP, Engelhart AE, Nanjunda RK, Wilson WD, Hud NV. Submicromolar, selective G-quadruplex ligands from one pot: thermodynamic and structural studies of human telomeric DNA binding by azacyanines. Chembiochem 2008 Aug 11; 9(12):1889-92.

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