Publications

    2016
  1. Pulivarthy SR, Lion M, Kuzu G, Matthews AG, Borowsky ML, Morris J, Kingston RE, Dennis JH, Tolstorukov MY, Oettinger MA. Regulated large-scale nucleosome density patterns and precise nucleosome positioning correlate with V(D)J recombination. Proc. Natl. Acad. Sci. U.S.A. 2016 Oct 18; 113(42):E6427-E6436.

  2. West JA, Mito M, Kurosaka S, Takumi T, Tanegashima C, Chujo T, Yanaka K, Kingston RE, Hirose T, Bond C, Fox A, Nakagawa S. Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization. J. Cell Biol. 2016 Sep 26; 214(7):817-30.

  3. Ray MK, Wiskow O, King MJ, Ismail N, Ergun A, Wang Y, Plys AJ, Davis CP, Kathrein K, Sadreyev R, Borowsky ML, Eggan K, Zon L, Galloway JL, Kingston RE. CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development. J. Biol. Chem. 2016 Sep 9; 291(37):19558-72.

  4. Deaton AM, Mieczkowski J, Tolstorukov MY, Kundu S, Sadreyev RI, Jansen LE, Kingston RE. Enhancer regions show high histone H3.3 turnover that changes during differentiation. Elife 2016 Jun 15; 5

  5. Mieczkowski J, Cook A, Bowman SK, Mueller B, Alver BH, Kundu S, Deaton AM, Urban JA, Larschan E, Park PJ, Kingston RE, Tolstorukov MY. MNase titration reveals differences between nucleosome occupancy and chromatin accessibility. Nat Commun 2016 May 06; 7:11485.

  6. Yildirim O, Kingston RE. Molecular Dissection of Chromatin Maturation via Click Chemistry. Curr Protoc Mol Biol 2016 Apr 01; 114:21.33.1-21.33.11.

  7. Wani AH, Boettiger AN, Schorderet P, Ergun A, Münger C, Sadreyev RI, Zhuang X, Kingston RE, Francis NJ. Chromatin topology is coupled to Polycomb group protein subnuclear organization. Nat Commun 2016 Jan 13; 7:10291.

  8. 2015
  9. Cajigas I, Leib DE, Cochrane J, Luo H, Swyter KR, Chen S, Clark BS, Thompson J, Yates JR, Kingston RE, Kohtz JD. Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling. Development 2015 Aug 1; 142(15):2641-52.

  10. Lei I, West J, Yan Z, Gao X, Fang P, Dennis JH, Gnatovskiy L, Wang W, Kingston RE. BAF250a Protein Regulates Nucleosome Occupancy and Histone Modifications in Priming Embryonic Stem Cell Differentiation. J. Biol. Chem. 2015 Jul 31; 290(31):19343-52.

  11. 2014
  12. Kingston RE, Tamkun JW. Transcriptional regulation by trithorax-group proteins. Cold Spring Harb Perspect Biol 2014 Oct; 6(10):a019349.

  13. West JA, Davis CP, Sunwoo H, Simon MD, Sadreyev RI, Wang PI, Tolstorukov MY, Kingston RE. The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites. Mol. Cell 2014 Sep 4; 55(5):791-802.

  14. Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, Egelhofer TA, Hu SS, Alekseyenko AA, Rechtsteiner A, Asker D, Belsky JA, Bowman SK, Chen QB, Day DS, Dong Y, Dose AC, Duan X, Epstein CB, Ercan S, Feingold EA, Ferrari F, Garrigues JM, Gehlenborg N, Good PJ, Haseley P, He D, Herrmann M, Hoffman MM, Jeffers TE, Kharchenko PV, Kolasinska-Zwierz P, Kotwaliwale CV, Kumar N, Langley SA, Larschan EN, Latorre I, Libbrecht MW, Lin X, Park R, Pazin MJ, Pham HN, Plachetka A, Qin B, Schwartz YB, Shoresh N, Stempor P, Vielle A, Wang C, Whittle CM, Xue H, Kingston RE, Kim JH, Bernstein BE, Dernburg AF, Pirrotta V, Kuroda MI, Noble WS, Tullius TD, Kellis M, MacAlpine DM, Strome S, Elgin SC, Lieb JD, Ahringer J, Karpen GH. Comparative analysis of metazoan chromatin organization. Nature 2014 Aug 28; 512(7515):449-52.

  15. Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco A, Chen S, Stützer A, Armache KJ, Simon MD, Xu C, Ali M, Murn J, Prisic S, Kutateladze TG, Vakoc CR, Min J, Kingston RE, Fischle W, Warren ST, Page DC, Shi Y. A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response. Cell 2014 May 8; 157(4):869-81.

  16. Sexton BS, Avey D, Druliner BR, Fincher JA, Vera DL, Grau DJ, Borowsky ML, Gupta S, Girimurugan SB, Chicken E, Zhang J, Noble WS, Zhu F, Kingston RE, Dennis JH. The spring-loaded genome: nucleosome redistributions are widespread, transient, and DNA-directed. Genome Res. 2014 Feb; 24(2):251-9.

  17. Bowman SK, Deaton AM, Domingues H, Wang PI, Sadreyev RI, Kingston RE, Bender W. H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex. Elife 2014; 3:e02833.

  18. West JA, Cook A, Alver BH, Stadtfeld M, Deaton AM, Hochedlinger K, Park PJ, Tolstorukov MY, Kingston RE. Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming. Nat Commun 2014; 5:4719.

  19. 2013
  20. Simon MD, Pinter SF, Fang R, Sarma K, Rutenberg-Schoenberg M, Bowman SK, Kesner BA, Maier VK, Kingston RE, Lee JT. High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation. Nature 2013 Dec 19; 504(7480):465-9.

  21. Toiber D, Erdel F, Bouazoune K, Silberman DM, Zhong L, Mulligan P, Sebastian C, Cosentino C, Martinez-Pastor B, Giacosa S, D'Urso A, Näär AM, Kingston R, Rippe K, Mostoslavsky R. SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling. Mol. Cell 2013 Aug 22; 51(4):454-68.

  22. Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. Variable Requirements for DNA-Binding Proteins at Polycomb-Dependent Repressive Regions in Human HOX Clusters. Mol. Cell. Biol. 2013 Aug; 33(16):3274-85.

  23. Riedel CG, Dowen RH, Lourenco GF, Kirienko NV, Heimbucher T, West JA, Bowman SK, Kingston RE, Dillin A, Asara JM, Ruvkun G. DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nat. Cell Biol. 2013 May; 15(5):491-501.

  24. Simon JA, Kingston RE. Occupying chromatin: polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Mol. Cell 2013 Mar 7; 49(5):808-24.

  25. Fang R, Chen F, Dong Z, Hu D, Barbera AJ, Clark EA, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Wang P, Simon MD, Zhou Q, Marynick MP, Lu H, Kaiser UB, Kingston RE, Shi YG. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation. Mol. Cell 2013 Feb 7; 49(3):558-70.

  26. Bouazoune K, Kingston RE. Assembly, remodelled. Elife 2013; 2:e01270.

  27. Bowman SK, Simon MD, Deaton AM, Tolstorukov M, Borowsky ML, Kingston RE. Multiplexed Illumina sequencing libraries from picogram quantities of DNA. BMC Genomics 2013; 14:466.

  28. 2012
  29. Bouazoune K, Kingston RE. Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders. Proc. Natl. Acad. Sci. U.S.A. 2012 Nov 20; 109(47):19238-43.

  30. Tolstorukov MY, Goldman JA, Gilbert C, Ogryzko V, Kingston RE, Park PJ. Histone Variant H2A.Bbd Is Associated with Active Transcription and mRNA Processing in Human Cells. Mol. Cell 2012 Aug 24; 47(4):596-607.

  31. Antão JM, Mason JM, Déjardin J, Kingston RE. Protein Landscape at Drosophila melanogaster Telomere-Associated Sequence Repeats. Mol. Cell. Biol. 2012 Jun; 32(12):2170-82.

  32. 2011
  33. Simon MD, Wang CI, Kharchenko PV, West JA, Chapman BA, Alekseyenko AA, Borowsky ML, Kuroda MI, Kingston RE. The genomic binding sites of a noncoding RNA. Proc. Natl. Acad. Sci. U.S.A. 2011 Dec 20; 108(51):20497-502.

  34. Armache KJ, Garlick JD, Canzio D, Narlikar GJ, Kingston RE. Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution. Science 2011 Nov 18; 334(6058):977-82.

  35. Grau DJ, Chapman BA, Garlick JD, Borowsky M, Francis NJ, Kingston RE. Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge. Genes Dev. 2011 Oct 15; 25(20):2210-21.

  36. 2010
  37. Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K, Song JJ, Kingston RE, Borowsky M, Lee JT. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol. Cell 2010 Dec 22; 40(6):939-53.

  38. Koh AS, Kingston RE, Benoist C, Mathis D. Global relevance of Aire binding to hypomethylated lysine-4 of histone-3. Proc. Natl. Acad. Sci. U.S.A. 2010 Jul 20; 107(29):13016-21.

  39. Seong IS, Woda JM, Song JJ, Lloret A, Abeyrathne PD, Woo CJ, Gregory G, Lee JM, Wheeler VC, Walz T, Kingston RE, Gusella JF, Conlon RA, MacDonald ME. Huntingtin facilitates polycomb repressive complex 2. Hum. Mol. Genet. 2010 Feb 15; 19(4):573-83.

  40. Goldman JA, Garlick JD, Kingston RE. Chromatin remodeling by imitation switch (ISWI) class ATP-dependent remodelers is stimulated by histone variant H2A.Z. J. Biol. Chem. 2010 Feb 12; 285(7):4645-51.

  41. Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. A region of the human HOXD cluster that confers polycomb-group responsiveness. Cell 2010 Jan 8; 140(1):99-110.

  42. 2009
  43. Lavigne M, Eskeland R, Azebi S, Saint-André V, Jang SM, Batsché E, Fan HY, Kingston RE, Imhof A, Muchardt C. Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression. PLoS Genet. 2009 Dec; 5(12):e1000769.

  44. Lau NC, Ohsumi T, Borowsky M, Kingston RE, Blower MD. Systematic and single cell analysis of Xenopus Piwi-interacting RNAs and Xiwi. EMBO J. 2009 Oct 7; 28(19):2945-58.

  45. Simon JA, Kingston RE. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat. Rev. Mol. Cell Biol. 2009 Oct; 10(10):697-708.

  46. Bouazoune K, Miranda TB, Jones PA, Kingston RE. Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF. Nucleic Acids Res. 2009 Sep; 37(16):5279-94.

  47. Tolstorukov MY, Kharchenko PV, Goldman JA, Kingston RE, Park PJ. Comparative analysis of H2A.Z nucleosome organization in the human and yeast genomes. Genome Res. 2009 Jun; 19(6):967-77.

  48. Mortensen RM, Kingston RE. Selection of transfected mammalian cells. Curr Protoc Mol Biol 2009 Apr; Chapter 9:Unit9.5.

  49. Déjardin J, Kingston RE. Purification of proteins associated with specific genomic Loci. Cell 2009 Jan 9; 136(1):175-86.

  50. 2008
  51. Song JJ, Kingston RE. WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket. J. Biol. Chem. 2008 Dec 12; 283(50):35258-64.

  52. Koh AS, Kuo AJ, Park SY, Cheung P, Abramson J, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, Benoist C, Mathis D. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific au Proc. Natl. Acad. Sci. U.S.A. 2008 Oct 14; 105(41):15878-83.

  53. Madhani HD, Francis NJ, Kingston RE, Kornberg RD, Moazed D, Narlikar GJ, Panning B, Struhl K. Epigenomics: a roadmap, but to where? Science 2008 Oct 3; 322(5898):43-4.

  54. Kharchenko PV, Woo CJ, Tolstorukov MY, Kingston RE, Park PJ. Nucleosome positioning in human HOX gene clusters. Genome Res. 2008 Oct; 18(10):1554-61.

  55. Gupta S, Dennis J, Thurman RE, Kingston R, Stamatoyannopoulos JA, Noble WS. Predicting human nucleosome occupancy from primary sequence. PLoS Comput. Biol. 2008; 4(8):e1000134.

  56. He X, Fan HY, Garlick JD, Kingston RE. Diverse regulation of SNF2h chromatin remodeling by noncatalytic subunits. Biochemistry 2008 Jul 8; 47(27):7025-33.

  57. Song JJ, Garlick JD, Kingston RE. Structural basis of histone H4 recognition by p55. Genes Dev. 2008 May 15; 22(10):1313-8.

  58. Trotter KW, Fan HY, Ivey ML, Kingston RE, Archer TK. The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activati Mol. Cell. Biol. 2008 Feb; 28(4):1413-26.

  59. 2007
  60. Dunn RK, Kingston RE. Gene regulation in the postgenomic era: technology takes the wheel. Mol. Cell 2007 Dec 14; 28(5):708-14.

  61. Woo CJ, Kingston RE. HOTAIR lifts noncoding RNAs to new levels. Cell 2007 Jun 29; 129(7):1257-9.

  62. Seto AG, Kingston RE, Lau NC. The coming of age for Piwi proteins. Mol. Cell 2007 Jun 8; 26(5):603-9.

  63. Dennis JH, Fan HY, Reynolds SM, Yuan G, Meldrim JC, Richter DJ, Peterson DG, Rando OJ, Noble WS, Kingston RE. Independent and complementary methods for large-scale structural analysis of mammalian chromatin. Genome Res. 2007 Jun; 17(6):928-39.

  64. Zhang Z, Fan HY, Goldman JA, Kingston RE. Homology-driven chromatin remodeling by human RAD54. Nat. Struct. Mol. Biol. 2007 May; 14(5):397-405.

  65. 2006
  66. He X, Fan HY, Narlikar GJ, Kingston RE. Human ACF1 alters the remodeling strategy of SNF2h. J. Biol. Chem. 2006 Sep 29; 281(39):28636-47.

  67. Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE. Characterization of the piRNA complex from rat testes. Science 2006 Jul 21; 313(5785):363-7.

  68. 2005
  69. Mahajan MC, Narlikar GJ, Boyapaty G, Kingston RE, Weissman SM. Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locu Proc. Natl. Acad. Sci. U.S.A. 2005 Oct 18; 102(42):15012-7.

  70. King IF, Emmons RB, Francis NJ, Wild B, Müller J, Kingston RE, Wu CT. Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function. Mol. Cell. Biol. 2005 Aug; 25(15):6578-91.

  71. Fan HY, Trotter KW, Archer TK, Kingston RE. Swapping function of two chromatin remodeling complexes. Mol. Cell 2005 Mar 18; 17(6):805-15.

  72. 2004
  73. Francis NJ, Kingston RE, Woodcock CL. Chromatin compaction by a polycomb group protein complex. Science 2004 Nov 26; 306(5701):1574-7.

  74. Levine SS, King IF, Kingston RE. Division of labor in polycomb group repression. Trends Biochem. Sci. 2004 Sep; 29(9):478-85.

  75. Peterson AJ, Mallin DR, Francis NJ, Ketel CS, Stamm J, Voeller RK, Kingston RE, Simon JA. Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression. Genetics 2004 Jul; 167(3):1225-39.

  76. Trinklein ND, Chen WC, Kingston RE, Myers RM. Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during the Cell Stress Chaperones 2004 Mar; 9(1):21-8.

  77. Lavigne M, Francis NJ, King IF, Kingston RE. Propagation of silencing; recruitment and repression of naive chromatin in trans by polycomb repressed chromatin. Mol. Cell 2004 Feb 13; 13(3):415-25.

  78. Fan HY, Narlikar GJ, Kingston RE. Noncovalent modification of chromatin: different remodeled products with different ATPase domains. Cold Spring Harb. Symp. Quant. Biol. 2004; 69:183-92.

  79. 2003
  80. Mulholland NM, King IF, Kingston RE. Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA. Genes Dev. 2003 Nov 15; 17(22):2741-6.

  81. Alexander JL, Rustom R, Herrington CS, Kingston RE, Bone JM. Nephroquiz: a woman with renal failure, ureteric obstruction and vasculitic rash. Nephrol. Dial. Transplant. 2003 Nov; 18(11):2439-41.

  82. He H, Soncin F, Grammatikakis N, Li Y, Siganou A, Gong J, Brown SA, Kingston RE, Calderwood SK. Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress. J. Biol. Chem. 2003 Sep 12; 278(37):35465-75.

  83. Kapoor DS, Tincello DG, Kingston RE. Life-threatening obstetric haemorrhage in second trimester from a placenta percreta with raised alpha-fetoprotein levels. J Obstet Gynaecol 2003 Sep; 23(5):570-1.

  84. Kingston RE, Chen CA, Okayama H. Calcium phosphate transfection. Curr Protoc Cell Biol 2003 Aug; Chapter 20:Unit 20.3.

  85. Kingston RE, Chen CA, Rose JK. Calcium phosphate transfection. Curr Protoc Mol Biol 2003 Aug; Chapter 9:Unit 9.1.

  86. Corey LL, Weirich CS, Benjamin IJ, Kingston RE. Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. Genes Dev. 2003 Jun 1; 17(11):1392-401.

  87. Fan HY, He X, Kingston RE, Narlikar GJ. Distinct strategies to make nucleosomal DNA accessible. Mol. Cell 2003 May; 11(5):1311-22.

  88. Mortensen R, Chesnut JD, Hoeffler JP, Kingston RE. Selection of transfected mammalian cells. Curr Protoc Mol Biol 2003 May; Chapter 9:Unit 9.5.

  89. Kirwan JM, Tincello DG, Lavender T, Kingston RE. How doctors record breaking bad news in ovarian cancer. Br. J. Cancer 2003 Mar 24; 88(6):839-42.

  90. Grau DJ, Antao JM, Kingston RE. Functional dissection of Polycomb repressive complex 1 reveals the importance of a charged domain. Cold Spring Harb. Symp. Quant. Biol. 2010; 75:61-70.

  91. 2002
  92. Rottbauer W, Saurin AJ, Lickert H, Shen X, Burns CG, Wo ZG, Kemler R, Kingston R, Wu C, Fishman M. Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell 2002 Nov 27; 111(5):661-72.

  93. King IF, Francis NJ, Kingston RE. Native and recombinant polycomb group complexes establish a selective block to template accessibility to repress transcriptio Mol. Cell. Biol. 2002 Nov; 22(22):7919-28.

  94. Kingston RE, Kaufman RJ, Bebbington CR, Rolfe MR. Amplification using CHO cell expression vectors. Curr Protoc Mol Biol 2002 Nov; Chapter 16:Unit 16.23.

  95. Müller J, Hart CM, Francis NJ, Vargas ML, Sengupta A, Wild B, Miller EL, O'Connor MB, Kingston RE, Simon JA. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 2002 Oct 18; 111(2):197-208.

  96. Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, Kingston RE. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol. Cell. Biol. 2002 Sep; 22(17):6070-8.

  97. Aoyagi S, Narlikar G, Zheng C, Sif S, Kingston RE, Hayes JJ. Nucleosome remodeling by the human SWI/SNF complex requires transient global disruption of histone-DNA interactions. Mol. Cell. Biol. 2002 Jun; 22(11):3653-62.

  98. Narlikar GJ, Fan HY, Kingston RE. Cooperation between complexes that regulate chromatin structure and transcription. Cell 2002 Feb 22; 108(4):475-87.

  99. Kirwan JM, Tincello DG, Herod JJ, Frost O, Kingston RE. Effect of delays in primary care referral on survival of women with epithelial ovarian cancer: retrospective audit. BMJ 2002 Jan 19; 324(7330):148-51.

  100. 2001
  101. Schnitzler GR, Cheung CL, Hafner JH, Saurin AJ, Kingston RE, Lieber CM. Direct imaging of human SWI/SNF-remodeled mono- and polynucleosomes by atomic force microscopy employing carbon nanotube tips Mol. Cell. Biol. 2001 Dec; 21(24):8504-11.

  102. Narlikar GJ, Phelan ML, Kingston RE. Generation and interconversion of multiple distinct nucleosomal states as a mechanism for catalyzing chromatin fluidity. Mol. Cell 2001 Dec; 8(6):1219-30.

  103. King IF, Kingston RE. Specifying transcription. Nature ; 414(6866):858-61.

  104. Aalfs JD, Narlikar GJ, Kingston RE. Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H. J. Biol. Chem. 2001 Sep 7; 276(36):34270-8.

  105. Francis NJ, Saurin AJ, Shao Z, Kingston RE. Reconstitution of a functional core polycomb repressive complex. Mol. Cell 2001 Sep; 8(3):545-56.

  106. Sullivan EK, Weirich CS, Guyon JR, Sif S, Kingston RE. Transcriptional activation domains of human heat shock factor 1 recruit human SWI/SNF. Mol. Cell. Biol. 2001 Sep; 21(17):5826-37.

  107. Saurin AJ, Shao Z, Erdjument-Bromage H, Tempst P, Kingston RE. A Drosophila Polycomb group complex includes Zeste and dTAFII proteins. Nature 2001 Aug 9; 412(6847):655-60.

  108. Francis NJ, Kingston RE. Mechanisms of transcriptional memory. Nat. Rev. Mol. Cell Biol. 2001 Jun; 2(6):409-21.

  109. Jónsson ZO, Dhar SK, Narlikar GJ, Auty R, Wagle N, Pellman D, Pratt RE, Kingston R, Dutta A. Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J. Biol. Chem. 2001 May 11; 276(19):16279-88.

  110. Kingston RE, Chen CA, Okayama H. Calcium phosphate transfection. Curr Protoc Neurosci 2001 May; Appendix 1:Appendix 1C.

  111. Ribaudo R, Gilman M, Kingston RE, Chomczynski P, Sacchi N. Preparation of RNA from tissues and cells. Curr Protoc Neurosci 2001 May; Appendix 1:Appendix 1I.

  112. Mortensen R, Chestnut JD, Hoeffler JP, Kingston RE. Selection of transfected mammalian cells. Curr Protoc Neurosci 2001 May; Chapter 4:Unit 4.6.

  113. Ribaudo R, Gilman M, Kingston RE, Choczynski P, Sacchi N. Preparation of RNA from tissues and cells. Curr Protoc Immunol 2001 May; Chapter 10:Unit 10.11.

  114. Kingston RE, Chen CA, Okayama H. Calcium phosphate transfection. Curr Protoc Immunol 2001 May; Chapter 10:Unit 10.13.

  115. Kingston RE. Stable transfer of genes into mammalian cells. Curr Protoc Immunol 2001 May; Chapter 10:Unit 10.17A.

  116. Brenowitz M, Senear DF, Kingston RE. DNase I footprint analysis of protein-DNA binding. Curr Protoc Mol Biol 2001 May; Chapter 12:Unit 12.4.

  117. Kingston RE, Chomczynski P, Sacchi N. Guanidine methods for total RNA preparation. Curr Protoc Mol Biol 2001 May; Chapter 4:Unit4.2.

  118. Kingston RE. Preparation of poly(A)+ RNA. Curr Protoc Mol Biol 2001 May; Chapter 4:Unit4.5.

  119. Kingston RE, Sheen J, Moore D. Isotopic assays for reporter gene activity. Curr Protoc Mol Biol 2001 May; Chapter 9:Unit9.7A.

  120. Kingston RE. Direct analysis of RNA after transfection. Curr Protoc Mol Biol 2001 May; Chapter 9:Unit9.8.

  121. Kingston RE, Sheen J, Moore D. Isotopic assays for reporter gene activity. Curr Protoc Pharmacol 2001 May; Chapter 6:Unit 6.4.

  122. Sif S, Saurin AJ, Imbalzano AN, Kingston RE. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. Genes Dev. 2001 Mar 1; 15(5):603-18.

  123. Guyon JR, Narlikar GJ, Sullivan EK, Kingston RE. Stability of a human SWI-SNF remodeled nucleosomal array. Mol. Cell. Biol. 2001 Feb; 21(4):1132-44.

  124. 2000
  125. Havas K, Flaus A, Phelan M, Kingston R, Wade PA, Lilley DM, Owen-Hughes T. Generation of superhelical torsion by ATP-dependent chromatin remodeling activities. Cell 2000 Dec 22; 103(7):1133-42.

  126. Aalfs JD, Kingston RE. What does 'chromatin remodeling' mean? Trends Biochem. Sci. 2000 Nov; 25(11):548-55.

  127. Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol. Cell 2000 Nov; 6(5):1037-48.

  128. DiRenzo J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M. BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Mol. Cell. Biol. 2000 Oct; 20(20):7541-9.

  129. Citterio E, Van Den Boom V, Schnitzler G, Kanaar R, Bonte E, Kingston RE, Hoeijmakers JH, Vermeulen W. ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor. Mol. Cell. Biol. 2000 Oct; 20(20):7643-53.

  130. Kadam S, McAlpine GS, Phelan ML, Kingston RE, Jones KA, Emerson BM. Functional selectivity of recombinant mammalian SWI/SNF subunits. Genes Dev. 2000 Oct 1; 14(19):2441-51.

  131. Phelan ML, Schnitzler GR, Kingston RE. Octamer transfer and creation of stably remodeled nucleosomes by human SWI-SNF and its isolated ATPases. Mol. Cell. Biol. 2000 Sep; 20(17):6380-9.

  132. de La Serna IL, Carlson KA, Hill DA, Guidi CJ, Stephenson RO, Sif S, Kingston RE, Imbalzano AN. Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene. Mol. Cell. Biol. 2000 Apr; 20(8):2839-51.

  133. 1999
  134. Kingston RE, Narlikar GJ. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity. Genes Dev. 1999 Sep 15; 13(18):2339-52.

  135. Shao Z, Raible F, Mollaaghababa R, Guyon JR, Wu CT, Bender W, Kingston RE. Stabilization of chromatin structure by PRC1, a Polycomb complex. Cell 1999 Jul 9; 98(1):37-46.

  136. Lee KM, Sif S, Kingston RE, Hayes JJ. hSWI/SNF disrupts interactions between the H2A N-terminal tail and nucleosomal DNA. Biochemistry 1999 Jun 29; 38(26):8423-9.

  137. Kingston RE. A shared but complex bridge. Nature 1999 May 20; 399(6733):199-200.

  138. Guyon JR, Narlikar GJ, Sif S, Kingston RE. Stable remodeling of tailless nucleosomes by the human SWI-SNF complex. Mol. Cell. Biol. 1999 Mar; 19(3):2088-97.

  139. Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 1999 Mar; 10(3):345-55.

  140. Saltsman KA, Prentice HL, Kingston RE. Mutations in the Schizosaccharomyces pombe heat shock factor that differentially affect responses to heat and cadmium stress. Mol. Gen. Genet. 1999 Feb; 261(1):161-9.

  141. Phelan ML, Sif S, Narlikar GJ, Kingston RE. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Mol. Cell 1999 Feb; 3(2):247-53.

  142. 1998
  143. Tong JK, Hassig CA, Schnitzler GR, Kingston RE, Schreiber SL. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature 1998 Oct 29; 395(6705):917-21.

  144. Sif S, Stukenberg PT, Kirschner MW, Kingston RE. Mitotic inactivation of a human SWI/SNF chromatin remodeling complex. Genes Dev. 1998 Sep 15; 12(18):2842-51.

  145. Schnitzler G, Sif S, Kingston RE. Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state. Cell 1998 Jul 10; 94(1):17-27.

  146. Saltsman KA, Prentice HL, Kingston RE. The C-terminal hydrophobic repeat of Schizosaccharomyces pombe heat shock factor is not required for heat-induced DNA-binding Yeast 1998 Jun 15; 14(8):733-46.

  147. Brown SA, Weirich CS, Newton EM, Kingston RE. Transcriptional activation domains stimulate initiation and elongation at different times and via different residues. EMBO J. 1998 Jun 1; 17(11):3146-54.

  148. Workman JL, Kingston RE. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 1998; 67:545-79.

  149. Schnitzler GR, Sif S, Kingston RE. A model for chromatin remodeling by the SWI/SNF family. Cold Spring Harb. Symp. Quant. Biol. 1998; 63:535-43.

  150. Jiménez CR, Li KW, Dreisewerd K, Spijker S, Kingston R, Bateman RH, Burlingame AL, Smit AB, van Minnen J, Geraerts WP. Direct mass spectrometric peptide profiling and sequencing of single neurons reveals differential peptide patterns in a small neuronal network. Biochemistry 1998 Feb 17; 37(7):2070-6.

  151. 1997
  152. Tan LT, Jones B, Gee A, Kingston RE. An audit of the treatment of carcinoma of the uterine cervix using external beam radiotherapy and a single line source brachy Br J Radiol 1997 Dec; 70(840):1259-69.

  153. Brown SA, Kingston RE. Disruption of downstream chromatin directed by a transcriptional activator. Genes Dev. 1997 Dec 1; 11(23):3116-21.

  154. Kingston RE. A snapshot of a dynamic nuclear building block. Nat. Struct. Biol. 1997 Oct; 4(10):763-6.

  155. 1996
  156. Knauf U, Newton EM, Kyriakis J, Kingston RE. Repression of human heat shock factor 1 activity at control temperature by phosphorylation. Genes Dev. 1996 Nov 1; 10(21):2782-93.

  157. Bunker CA, Kingston RE. Activation domain-mediated enhancement of activator binding to chromatin in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 1996 Oct 1; 93(20):10820-5.

  158. Imbalzano AN, Schnitzler GR, Kingston RE. Nucleosome disruption by human SWI/SNF is maintained in the absence of continued ATP hydrolysis. J. Biol. Chem. 1996 Aug 23; 271(34):20726-33.

  159. Brown SA, Imbalzano AN, Kingston RE. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Genes Dev. 1996 Jun 15; 10(12):1479-90.

  160. Kingston RE, Bunker CA, Imbalzano AN. Repression and activation by multiprotein complexes that alter chromatin structure. Genes Dev. 1996 Apr 15; 10(8):905-20.

  161. Newton EM, Knauf U, Green M, Kingston RE. The regulatory domain of human heat shock factor 1 is sufficient to sense heat stress. Mol. Cell. Biol. 1996 Mar; 16(3):839-46.

  162. Tan LT, Jones B, Green JA, Kingston RE, Clark PI. Treatment of carcinomas of the uterine cervix which remain bulky after initial external beam radiotherapy: a pilot study usin Br J Radiol 1996 Feb; 69(818):165-71.

  163. Wilson CJ, Chao DM, Imbalzano AN, Schnitzler GR, Kingston RE, Young RA. RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell 1996 Jan 26; 84(2):235-44.

  164. 1995
  165. Green M, Schuetz TJ, Sullivan EK, Kingston RE. A heat shock-responsive domain of human HSF1 that regulates transcription activation domain function. Mol. Cell. Biol. 1995 Jun; 15(6):3354-62.

  166. Larson JS, Schuetz TJ, Kingston RE. In vitro activation of purified human heat shock factor by heat. Biochemistry 1995 Feb 14; 34(6):1902-11.

  167. Bunker CA, Kingston RE. Identification of a cDNA for SSRP1, an HMG-box protein, by interaction with the c-Myc oncoprotein in a novel bacterial expres Nucleic Acids Res. 1995 Jan 25; 23(2):269-76.

  168. 1994
  169. Kwon H, Imbalzano AN, Khavari PA, Kingston RE, Green MR. Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex. Nature 1994 Aug 11; 370(6489):477-81.

  170. Imbalzano AN, Kwon H, Green MR, Kingston RE. Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature 1994 Aug 11; 370(6489):481-5.

  171. Wechsler DS, Papoulas O, Dang CV, Kingston RE. Differential binding of c-Myc and Max to nucleosomal DNA. Mol. Cell. Biol. 1994 Jun; 14(6):4097-107.

  172. Kingston RE, Green MR. Modeling eukaryotic transcriptional activation. Curr. Biol. 1994 Apr 1; 4(4):325-32.

  173. Imbalzano AN, Zaret KS, Kingston RE. Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the TATA-binding protein for DNA. J. Biol. Chem. 1994 Mar 18; 269(11):8280-6.

  174. Bunker CA, Kingston RE. Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells. Mol. Cell. Biol. 1994 Mar; 14(3):1721-32.

  175. Jones B, Tan LT, Kingston R. HDR versus LDR gynaecological brachytherapy revisited. Radiother Oncol 1994 Feb; 30(2):186.

  176. Hsu HL, Huang L, Tsan JT, Funk W, Wright WE, Hu JS, Kingston RE, Baer R. Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins. Mol. Cell. Biol. 1994 Feb; 14(2):1256-65.

  177. 1993
  178. Sheldon LA, Kingston RE. Hydrophobic coiled-coil domains regulate the subcellular localization of human heat shock factor 2. Genes Dev. 1993 Aug; 7(8):1549-58.

  179. Jones B, Kingston R, Green J, Adams E, Bleasdale C. The effect of treatment duration in the local control of cervix cancer. Radiother Oncol 1993 Aug; 28(2):179-80.

  180. Gallo GJ, Prentice H, Kingston RE. Heat shock factor is required for growth at normal temperatures in the fission yeast Schizosaccharomyces pombe. Mol. Cell. Biol. 1993 Feb; 13(2):749-61.

  181. Juan LJ, Walter PP, Taylor IC, Kingston RE, Workman JL. Nucleosome cores and histone H1 in the binding of GAL4 derivatives and the reactivation of transcription from nucleosome temp Cold Spring Harb. Symp. Quant. Biol. 1993; 58:213-23.

  182. 1992
  183. Workman JL, Kingston RE. Nucleosome core displacement in vitro via a metastable transcription factor-nucleosome complex. Science 1992 Dec 11; 258(5089):1780-4.

  184. Prentice HL, Kingston RE. Mammalian promoter element function in the fission yeast Schizosaccharomyces pombe. Nucleic Acids Res. 1992 Jul 11; 20(13):3383-90.

  185. Papoulas O, Williams NG, Kingston RE. DNA binding activities of c-Myc purified from eukaryotic cells. J. Biol. Chem. 1992 May 25; 267(15):10470-80.

  186. Hu JS, Olson EN, Kingston RE. HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory fact Mol. Cell. Biol. 1992 Mar; 12(3):1031-42.

  187. Cheng LZ, Workman JL, Kingston RE, Kelly TJ. Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16. Proc. Natl. Acad. Sci. U.S.A. 1992 Jan 15; 89(2):589-93.

  188. 1991
  189. Liao SM, Taylor IC, Kingston RE, Young RA. RNA polymerase II carboxy-terminal domain contributes to the response to multiple acidic activators in vitro. Genes Dev. 1991 Dec; 5(12B):2431-40.

  190. Schuetz TJ, Gallo GJ, Sheldon L, Tempst P, Kingston RE. Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans. Proc. Natl. Acad. Sci. U.S.A. 1991 Aug 15; 88(16):6911-5.

  191. Taylor IC, Workman JL, Schuetz TJ, Kingston RE. Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains. Genes Dev. 1991 Jul; 5(7):1285-98.

  192. Workman JL, Taylor IC, Kingston RE. Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes. Cell 1991 Feb 8; 64(3):533-44.

  193. Gallo GJ, Schuetz TJ, Kingston RE. Regulation of heat shock factor in Schizosaccharomyces pombe more closely resembles regulation in mammals than in Saccharomyc Mol. Cell. Biol. 1991 Jan; 11(1):281-8.

  194. Workman JL, Taylor IC, Kingston RE, Roeder RG. Control of class II gene transcription during in vitro nucleosome assembly. Methods Cell Biol. 1991; 35:419-47.

  195. 1990
  196. Kaddurah-Daouk R, Lillie JW, Daouk GH, Green MR, Kingston R, Schimmel P. Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a. Mol. Cell. Biol. 1990 Apr; 10(4):1476-83.

  197. Greene JM, Kingston RE. TATA-dependent and TATA-independent function of the basal and heat shock elements of a human hsp70 promoter. Mol. Cell. Biol. 1990 Apr; 10(4):1319-28.

  198. Hensold JO, Hunt CR, Calderwood SK, Housman DE, Kingston RE. DNA binding of heat shock factor to the heat shock element is insufficient for transcriptional activation in murine erythrole Mol. Cell. Biol. 1990 Apr; 10(4):1600-8.

  199. Workman JL, Roeder RG, Kingston RE. An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin EMBO J. 1990 Apr; 9(4):1299-308.

  200. Taylor IC, Kingston RE. Factor substitution in a human HSP70 gene promoter: TATA-dependent and TATA-independent interactions. Mol. Cell. Biol. 1990 Jan; 10(1):165-75.

  201. Taylor IC, Kingston RE. E1a transactivation of human HSP70 gene promoter substitution mutants is independent of the composition of upstream and TATA Mol. Cell. Biol. 1990 Jan; 10(1):176-83.

  202. 1989
  203. Kingston RE. Transcription control and differentiation: the HLH family, c-myc and C/EBP. Curr. Opin. Cell Biol. 1989 Dec; 1(6):1081-7.

  204. Taylor IC, Solomon W, Weiner BM, Paucha E, Bradley M, Kingston RE. Stimulation of the human heat shock protein 70 promoter in vitro by simian virus 40 large T antigen. J. Biol. Chem. 1989 Sep 25; 264(27):16160-4.

  205. 1988
  206. Larson JS, Schuetz TJ, Kingston RE. Activation in vitro of sequence-specific DNA binding by a human regulatory factor. Nature 1988 Sep 22; 335(6188):372-5.

  207. Daouk GH, Kaddurah-Daouk R, Putney S, Kingston R, Schimmel P. Isolation of a functional human gene for brain creatine kinase. J. Biol. Chem. 1988 Feb 15; 263(5):2442-6.

  208. Nishigaki T, Hanaka S, Kingston RE, Handa H. A specific domain of the adenovirus EIV promoter is necessary to maintain susceptibility of the integrated promoter to EIA tr Mol. Cell. Biol. 1988 Jan; 8(1):353-60.

  209. 1987
  210. Greene JM, Larin Z, Taylor IC, Prentice H, Gwinn KA, Kingston RE. Multiple basal elements of a human hsp70 promoter function differently in human and rodent cell lines. Mol. Cell. Biol. 1987 Oct; 7(10):3646-55.

  211. Kaddurah-Daouk R, Greene JM, Baldwin AS, Kingston RE. Activation and repression of mammalian gene expression by the c-myc protein. Genes Dev. 1987 Jun; 1(4):347-57.

  212. Kingston RE, Schuetz TJ, Larin Z. Heat-inducible human factor that binds to a human hsp70 promoter. Mol. Cell. Biol. 1987 Apr; 7(4):1530-4.

  213. Morgan WD, Williams GT, Morimoto RI, Greene J, Kingston RE, Tjian R. Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a h Mol. Cell. Biol. 1987 Mar; 7(3):1129-38.

  214. Williams GT, Kingston R, Owen MJ, Jenkinson EJ. A single micromanipulated stem cell gives rise to multiple T-cell receptor gene rearrangements in the thymus in vitro. Nature ; 324(6092):63-4.

  215. 1986
  216. Kingston RE, Cowie A, Morimoto RI, Gwinn KA. Binding of polyomavirus large T antigen to the human hsp70 promoter is not required for trans activation. Mol. Cell. Biol. 1986 Sep; 6(9):3180-90.

  217. Wurm FM, Gwinn KA, Kingston RE. Inducible overproduction of the mouse c-myc protein in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 1986 Aug; 83(15):5414-8.

  218. Owen MJ, Jenkinson EJ, Williams GT, Kingston R. An investigation of T cell receptor gene rearrangement and expression in organ cultures of normal embryonic thymus and Thy-1+ Eur. J. Immunol. 1986 Jul; 16(7):875-8.

  219. Wu BJ, Kingston RE, Morimoto RI. Human HSP70 promoter contains at least two distinct regulatory domains. Proc. Natl. Acad. Sci. U.S.A. 1986 Feb; 83(3):629-33.

  220. 1985
  221. Kingston RE, Baldwin AS, Sharp PA. Transcription control by oncogenes. Cell 1985 May; 41(1):3-5.

  222. 1984
  223. Kingston RE, Baldwin AS, Sharp PA. Regulation of heat shock protein 70 gene expression by c-myc. Nature ; 312(5991):280-2.

  224. Kingston RE, Kaufman RJ, Sharp PA. Regulation of transcription of the adenovirus EII promoter by EIa gene products: absence of sequence specificity. Mol. Cell. Biol. 1984 Oct; 4(10):1970-7.

  225. 1983
  226. Handa H, Kingston RE, Sharp PA. Inhibition of adenovirus early region IV transcription in vitro by a purified viral DNA binding protein. Nature 1983 Apr 7; 302(5908):545-7.

  227. 1981
  228. Kingston RE, Chamberlin MJ. Pausing and attenuation of in vitro transcription in the rrnB operon of E. coli. Cell 1981 Dec; 27(3 Pt 2):523-31.

  229. Kingston RE, Gutell RR, Taylor AR, Chamberlin MJ. Transcriptional mapping of plasmid pKK3535. Quantitation of the effect of guanosine tetraphosphate on binding to the rrnB pro J. Mol. Biol. 1981 Mar 15; 146(4):433-49.

  230. Garlick RL, Shaeffer JR, Chapman PB, Kingston RE, Mazer JS, Bunn HF. Synthesis of acetylated human fetal hemoglobin. J. Biol. Chem. 1981 Feb 25; 256(4):1727-31.

  231. 1980
  232. Shaeffer JR, Schmidt GJ, Kingston RE, Bunn HF. Synthesis of hemoglobin Cranston, and elongated beta chain variant. J. Mol. Biol. 1980 Jul 5; 140(3):377-89.

  233. 1978
  234. Shaeffer JR, Kingston RE, McDonald MJ, Bunn HF. Competition of normal beta chains and sickle haemoglobin beta chains for alpha chains as a post-translational control mechani Nature 1978 Dec 7; 276(5688):631-3.

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