Ausubel Lab

Frederick Ausubel, Ph.D.

Department of Molecular Biology
Simches Research Center
Boston, MA 02114

Phone: (617) 726-5969
Fax: (617) 726-5949
Email

Website
Publications
    2013
  1. Djonovic S, Urbach JM, Drenkard E, Bush J, Feinbaum R, Ausubel JL, Traficante D, Risech M, Kocks C, Fischbach MA, Priebe GP. Trehalose Biosynthesis Promotes Pseudomonas aeruginosa Pathogenicity in Plants. PLoS Pathog. 2013 Mar; 9(3):e1003217.

  2. Cezairliyan B, Vinayavekhin N, Grenfell-Lee D, Yuen GJ, Saghatelian A, Ausubel FM. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans. PLoS Pathog. 2013 Jan; 9(1):e1003101.

  3. 2012
  4. Danna CH, Zhang XC, Khatri A, Bent AF, Ronald PC, Ausubel FM. FLS2-mediated responses to Ax21-derived peptides: response to the Mueller et al. commentary. Plant Cell 2012 Aug; 24(8):3174-6.

  5. Feinbaum RL, Urbach JM, Liberati NT, Djonovic S, Adonizio A, Carvunis AR, Ausubel FM. Genome-Wide Identification of Pseudomonas aeruginosa Virulence-Related Genes Using a Caenorhabditis elegans Infection Model. PLoS Pathog. 2012 Jul; 8(7):e1002813.

  6. Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE. An image analysis toolbox for high-throughput C. elegans assays. Nat. Methods 2012 Jul; 9(7):714-6.

  7. Yao Y, Danna CH, Ausubel FM, Kovalchuk I. Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants. Plant Signal Behav 2012 Jul; 7(7):741-5.

  8. Pukkila-Worley R, Feinbaum R, Kirienko NV, Larkins-Ford J, Conery AL, Ausubel FM. Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection. PLoS Genet. 2012 Jun; 8(6):e1002733.

  9. McEwan DL, Kirienko NV, Ausubel FM. Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans. Cell Host Microbe 2012 Apr 19; 11(4):364-74.

  10. O'Brien JA, Daudi A, Finch P, Butt VS, Whitelegge JP, Souda P, Ausubel FM, Bolwell GP. A peroxidase-dependent apoplastic oxidative burst in cultured Arabidopsis cells functions in MAMP-elicited defense. Plant Physiol. 2012 Apr; 158(4):2013-27.

  11. Pukkila-Worley R, Ausubel FM. Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium. Curr. Opin. Immunol. 2012 Feb; 24(1):3-9.

  12. Daudi A, Cheng Z, O'Brien JA, Mammarella N, Khan S, Ausubel FM, Bolwell GP. The apoplastic oxidative burst peroxidase in Arabidopsis is a major component of pattern-triggered immunity. Plant Cell 2012 Jan; 24(1):275-87.

  13. Whiteman NK, Gloss AD, Sackton TB, Groen SC, Humphrey PT, Lapoint RT, Sønderby IE, Halkier BA, Kocks C, Ausubel FM, Pierce NE. Genes involved in the evolution of herbivory by a leaf-mining, drosophilid fly. Genome Biol Evol 2012 Jan; 4(9):788-804.

  14. 2011
  15. Limmer S, Haller S, Drenkard E, Lee J, Yu S, Kocks C, Ausubel FM, Ferrandon D. Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model. Proc. Natl. Acad. Sci. U.S.A. 2011 Oct 18; 108(42):17378-83.

  16. Yao Y, Danna CH, Zemp FJ, Titov V, Ciftci ON, Przybylski R, Ausubel FM, Kovalchuk I. UV-C-irradiated Arabidopsis and tobacco emit volatiles that trigger genomic instability in neighboring plants. Plant Cell 2011 Oct; 23(10):3842-52.

  17. Slatko BE, Kieleczawa J, Ju J, Gardner AF, Hendrickson CL, Ausubel FM. "First generation" automated DNA sequencing technology. Curr Protoc Mol Biol 2011 Oct; Chapter 7:Unit7.2.

  18. Pukkila-Worley R, Ausubel FM, Mylonakis E. Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. PLoS Pathog. 2011 Jun; 7(6):e1002074.

  19. Danna CH, Millet YA, Koller T, Han SW, Bent AF, Ronald PC, Ausubel FM. The Arabidopsis flagellin receptor FLS2 mediates the perception of Xanthomonas Ax21 secreted peptides. Proc. Natl. Acad. Sci. U.S.A. 2011 May 31; 108(22):9286-91.

  20. Whiteman NK, Groen SC, Chevasco D, Bear A, Beckwith N, Gregory TR, Denoux C, Mammarella N, Ausubel FM, Pierce NE. Mining the plant-herbivore interface with a leafmining Drosophila of Arabidopsis. Mol. Ecol. 2011 Mar; 20(5):995-1014.

  21. Gopalan S, Ausubel FM. A high throughput amenable Arabidopsis-P. aeruginosa system reveals a rewired regulatory module and the utility to identify potent anti-infectives. PLoS ONE 2011; 6(1):e16381.

  22. 2010
  23. Tomkiewicz D, Casadei G, Larkins-Ford J, Moy TI, Garner J, Bremner JB, Ausubel FM, Lewis K, Kelso MJ. Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components. Antimicrob. Agents Chemother. 2010 Aug; 54(8):3219-24.

  24. Irazoqui JE, Ausubel FM. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Caenorhabditis elegans as a model to study tissues involved in host immunity and microbial pathogenesis. Clin. Exp. Immunol. 2010 Apr; 160(1):48-57.

  25. Millet YA, Danna CH, Clay NK, Songnuan W, Simon MD, Werck-Reichhart D, Ausubel FM. Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns. Plant Cell 2010 Mar; 22(3):973-90.

  26. Estes KA, Dunbar TL, Powell JR, Ausubel FM, Troemel ER. bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 2010 Feb 2; 107(5):2153-8.

  27. Irazoqui JE, Troemel ER, Feinbaum RL, Luhachack LG, Cezairliyan BO, Ausubel FM. Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus. PLoS Pathog. 2010; 6:e1000982.

  28. Irazoqui JE, Urbach JM, Ausubel FM. Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat. Rev. Immunol. 2010 Jan; 10(1):47-58.

  29. Raviv TR, Ljosa V, Conery AL, Ausubel FM, Carpenter AE, Golland P, Wählby C. Morphology-guided graph search for untangling objects: C. elegans analysis. Med Image Comput Comput Assist Interv 2010; 13(Pt 3):634-41.

  30. 2009
  31. Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM. High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chem. Biol. 2009 Jul 17; 4(7):527-33.

  32. Urbach JM, Wei T, Liberati N, Grenfell-Lee D, Villanueva J, Wu G, Ausubel FM. Using PATIMDB to create bacterial transposon insertion mutant libraries. Curr Protoc Mol Biol 2009 Apr; Chapter 19:Unit 19.7.

  33. Chandran D, Tai YC, Hather G, Dewdney J, Denoux C, Burgess DG, Ausubel FM, Speed TP, Wildermuth MC. Temporal global expression data reveal known and novel salicylate-impacted processes and regulators mediating powdery mildew growth and reproduction on Arabidopsis. Plant Physiol. 2009 Mar; 149(3):1435-51.

  34. Powell JR, Kim DH, Ausubel FM. The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response. Proc. Natl. Acad. Sci. U.S.A. 2009 Feb 24; 106(8):2782-7.

  35. Clay NK, Adio AM, Denoux C, Jander G, Ausubel FM. Glucosinolate metabolites required for an Arabidopsis innate immune response. Science 2009 Jan 2; 323(5910):95-101.

  36. Okoli I, Coleman JJ, Tampakakis E, Tempakakis E, An WF, Holson E, Wagner F, Conery AL, Larkins-Ford J, Wu G, Stern A, Ausubel FM, Mylonakis E. Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay. PLoS ONE 2009; 4(9):e7025.

  37. 2008
  38. Troemel ER, Félix MA, Whiteman NK, Barrière A, Ausubel FM. Microsporidia are natural intracellular parasites of the nematode Caenorhabditis elegans. PLoS Biol. 2008 Dec 9; 6(12):2736-52.

  39. Irazoqui JE, Ng A, Xavier RJ, Ausubel FM. Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions. Proc. Natl. Acad. Sci. U.S.A. 2008 Nov 11; 105(45):17469-74.

  40. Galletti R, Denoux C, Gambetta S, Dewdney J, Ausubel FM, De Lorenzo G, Ferrari S. The AtrbohD-mediated oxidative burst elicited by oligogalacturonides in Arabidopsis is dispensable for the activation of defense responses effective against Botrytis cinerea. Plant Physiol. 2008 Nov; 148(3):1695-706.

  41. Adonizio A, Leal SM, Ausubel FM, Mathee K. Attenuation of Pseudomonas aeruginosa virulence by medicinal plants in a Caenorhabditis elegans model system. J. Med. Microbiol. 2008 Jul; 57(Pt 7):809-13.

  42. Lemaitre B, Ausubel FM. Animal models for host-pathogen interactions. Curr. Opin. Microbiol. 2008 Jun; 11(3):249-50.

  43. Denoux C, Galletti R, Mammarella N, Gopalan S, Werck D, De Lorenzo G, Ferrari S, Ausubel FM, Dewdney J. Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings. Mol Plant 2008 May; 1(3):423-45.

  44. Miyata S, Begun J, Troemel ER, Ausubel FM. DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans. Genetics 2008 Feb; 178(2):903-18.

  45. Gopalan S, Ausubel FM. A metasystem of framework model organisms to study emergence of new host-microbe adaptations. PLoS ONE 2008; 3(12):e3891.

  46. Powell JR, Ausubel FM. Models of Caenorhabditis elegans infection by bacterial and fungal pathogens. Methods Mol. Biol. 2008; 415:403-27.

  47. Liberati NT, Urbach JM, Thurber TK, Wu G, Ausubel FM. Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality. Methods Mol. Biol. 2008; 416:153-69.

  48. 2007
  49. Kuchma SL, Brothers KM, Merritt JH, Liberati NT, Ausubel FM, O'Toole GA. BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14. J. Bacteriol. 2007 Nov; 189(22):8165-78.

  50. Mylonakis E, Casadevall A, Ausubel FM. Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi. PLoS Pathog. 2007 Jul 27; 3(7):e101.

  51. Mooij MJ, Drenkard E, Llamas MA, Vandenbroucke-Grauls CM, Savelkoul PH, Ausubel FM, Bitter W. Characterization of the integrated filamentous phage Pf5 and its involvement in small-colony formation. Microbiology (Reading, Engl.) 2007 Jun; 153(Pt 6):1790-8.

  52. Ferrari S, Galletti R, Denoux C, De Lorenzo G, Ausubel FM, Dewdney J. Resistance to Botrytis cinerea induced in Arabidopsis by elicitors is independent of salicylic acid, ethylene, or jasmonate signaling but requires PHYTOALEXIN DEFICIENT3. Plant Physiol. 2007 May; 144(1):367-79.

  53. Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM, Sifri CD. Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. PLoS Pathog. 2007 Apr; 3(4):e57.

  54. Breger J, Fuchs BB, Aperis G, Moy TI, Ausubel FM, Mylonakis E. Antifungal chemical compounds identified using a C. elegans pathogenicity assay. PLoS Pathog. 2007 Feb; 3(2):e18.

  55. 2006
  56. Lewis K, Ausubel FM. Prospects for plant-derived antibacterials. Nat. Biotechnol. 2006 Dec; 24(12):1504-7.

  57. Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, Kim DH. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet. 2006 Nov 10; 2(11):e183.

  58. Ball AR, Casadei G, Samosorn S, Bremner JB, Ausubel FM, Moy TI, Lewis K. Conjugating berberine to a multidrug efflux pump inhibitor creates an effective antimicrobial. ACS Chem. Biol. 2006 Oct 24; 1(9):594-600.

  59. Bindschedler LV, Dewdney J, Blee KA, Stone JM, Asai T, Plotnikov J, Denoux C, Hayes T, Gerrish C, Davies DR, Ausubel FM, Bolwell GP. Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. Plant J. 2006 Sep; 47(6):851-63.

  60. Moy TI, Ball AR, Anklesaria Z, Casadei G, Lewis K, Ausubel FM. Identification of novel antimicrobials using a live-animal infection model. Proc. Natl. Acad. Sci. U.S.A. 2006 Jul 5; 103(27):10414-9.

  61. Liberati NT, Urbach JM, Miyata S, Lee DG, Drenkard E, Wu G, Villanueva J, Wei T, Ausubel FM. An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants. Proc. Natl. Acad. Sci. U.S.A. 2006 Feb 21; 103(8):2833-8.

  62. Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S. Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence. Proc. Natl. Acad. Sci. U.S.A. 2006 Feb 21; 103(8):2839-44.

  63. Bush J, Jander G, Ausubel FM. Prevention and control of pests and diseases. Methods Mol. Biol. 2006; 323:13-25.

  64. Lee DG, Urbach JM, Wu G, Liberati NT, Feinbaum RL, Miyata S, Diggins LT, He J, Saucier M, Déziel E, Friedman L, Li L, Grills G, Montgomery K, Kucherlapati R, Rahme LG, Ausubel FM. Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol. 2006; 7(10):R90.

  65. 2005
  66. Ausubel FM. Are innate immune signaling pathways in plants and animals conserved? Nat. Immunol. 2005 Oct; 6(10):973-9.

  67. Diener AC, Ausubel FM. RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific. Genetics 2005 Sep; 171(1):305-21.

  68. Mylonakis E, Moreno R, El Khoury JB, Idnurm A, Heitman J, Calderwood SB, Ausubel FM, Diener A. Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infect. Immun. 2005 Jul; 73(7):3842-50.

  69. Sifri CD, Begun J, Ausubel FM. The worm has turned--microbial virulence modeled in Caenorhabditis elegans. Trends Microbiol. 2005 Mar; 13(3):119-27.

  70. Chang JH, Urbach JM, Law TF, Arnold LW, Hu A, Gombar S, Grant SR, Ausubel FM, Dangl JL. A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae. Proc. Natl. Acad. Sci. U.S.A. 2005 Feb 15; 102(7):2549-54.

  71. Begun J, Sifri CD, Goldman S, Calderwood SB, Ausubel FM. Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model. Infect. Immun. 2005 Feb; 73(2):872-7.

  72. Kim DH, Ausubel FM. Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Curr. Opin. Immunol. 2005 Feb; 17(1):4-10.

  73. Cui J, Bahrami AK, Pringle EG, Hernandez-Guzman G, Bender CL, Pierce NE, Ausubel FM. Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores. Proc. Natl. Acad. Sci. U.S.A. 2005 Feb 1; 102(5):1791-6.

  74. 2004
  75. Rojo E, Martín R, Carter C, Zouhar J, Pan S, Plotnikova J, Jin H, Paneque M, Sánchez-Serrano JJ, Baker B, Ausubel FM, Raikhel NV. VPEgamma exhibits a caspase-like activity that contributes to defense against pathogens. Curr. Biol. 2004 Nov 9; 14(21):1897-906.

  76. Garsin DA, Urbach J, Huguet-Tapia JC, Peters JE, Ausubel FM. Construction of an Enterococcus faecalis Tn917-mediated-gene-disruption library offers insight into Tn917 insertion patterns. J. Bacteriol. 2004 Nov; 186(21):7280-9.

  77. Mylonakis E, Idnurm A, Moreno R, El Khoury J, Rottman JB, Ausubel FM, Heitman J, Calderwood SB. Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. Mol. Microbiol. 2004 Oct; 54(2):407-19.

  78. Moy TI, Mylonakis E, Calderwood SB, Ausubel FM. Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium. Infect. Immun. 2004 Aug; 72(8):4512-20.

  79. Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM. Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc. Natl. Acad. Sci. U.S.A. 2004 Jul 27; 101(30):10990-4.

  80. Tenor JL, McCormick BA, Ausubel FM, Aballay A. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Curr. Biol. 2004 Jun 8; 14(11):1018-24.

  81. Mizuno T, Hisamoto N, Terada T, Kondo T, Adachi M, Nishida E, Kim DH, Ausubel FM, Matsumoto K. The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J. 2004 Jun 2; 23(11):2226-34.

  82. Engelbert M, Mylonakis E, Ausubel FM, Calderwood SB, Gilmore MS. Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis. Infect. Immun. 2004 Jun; 72(6):3628-33.

  83. Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc. Natl. Acad. Sci. U.S.A. 2004 Apr 27; 101(17):6593-8.

  84. Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB, Mylonakis E. Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. Eukaryotic Cell 2004 Apr; 3(2):413-9.

  85. 2003
  86. Ferrari S, Plotnikova JM, De Lorenzo G, Ausubel FM. Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4. Plant J. 2003 Jul; 35(2):193-205.

  87. Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science 2003 Jun 20; 300(5627):1921.

  88. Mylonakis E, Ausubel FM, Tang RJ, Calderwood SB. The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis. Expert Rev Anti Infect Ther 2003 Jun; 1(1):167-73.

  89. Miyata S, Casey M, Frank DW, Ausubel FM, Drenkard E. Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis. Infect. Immun. 2003 May; 71(5):2404-13.

  90. Sifri CD, Begun J, Ausubel FM, Calderwood SB. Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infect. Immun. 2003 Apr; 71(4):2208-17.

  91. Alonso JM, Stepanova AN, Solano R, Wisman E, Ferrari S, Ausubel FM, Ecker JR. Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A. 2003 Mar 4; 100(5):2992-7.

  92. Coleman FT, Mueschenborn S, Meluleni G, Ray C, Carey VJ, Vargas SO, Cannon CL, Ausubel FM, Pier GB. Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection. Proc. Natl. Acad. Sci. U.S.A. 2003 Feb 18; 100(4):1949-54.

  93. Aballay A, Drenkard E, Hilbun LR, Ausubel FM. Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway. Curr. Biol. 2003 Jan 8; 13(1):47-52.

  94. Ferrari S, Vairo D, Ausubel FM, Cervone F, De Lorenzo G. Tandemly duplicated Arabidopsis genes that encode polygalacturonase-inhibiting proteins are regulated coordinately by different signal transduction pathways in response to fungal infection. Plant Cell 2003 Jan; 15(1):93-106.

  95. 2002
  96. Mylonakis E, Ausubel FM, Perfect JR, Heitman J, Calderwood SB. Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc. Natl. Acad. Sci. U.S.A. 2002 Nov 26; 99(24):15675-80.

  97. Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB. Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice. Infect. Immun. 2002 Oct; 70(10):5647-50.

  98. Mylonakis E, Engelbert M, Qin X, Sifri CD, Murray BE, Ausubel FM, Gilmore MS, Calderwood SB. The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model. Infect. Immun. 2002 Aug; 70(8):4678-81.

  99. Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM. A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 2002 Jul 26; 297(5581):623-6.

  100. Ausubel F, Benfey P. Arabidopsis functional genomics. Plant Physiol. 2002 Jun; 129(2):393.

  101. Cui J, Jander G, Racki LR, Kim PD, Pierce NE, Ausubel FM. Signals involved in Arabidopsis resistance to Trichoplusia ni caterpillars induced by virulent and avirulent strains of the phytopathogen Pseudomonas syringae. Plant Physiol. 2002 Jun; 129(2):551-64.

  102. Drenkard E, Ausubel FM. Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Nature 2002 Apr 18; 416(6882):740-3.

  103. Kudva IT, Evans PS, Perna NT, Barrett TJ, Ausubel FM, Blattner FR, Calderwood SB. Strains of Escherichia coli O157:H7 differ primarily by insertions or deletions, not single-nucleotide polymorphisms. J. Bacteriol. 2002 Apr; 184(7):1873-9.

  104. Kudva IT, Evans PS, Perna NT, Barrett TJ, DeCastro GJ, Ausubel FM, Blattner FR, Calderwood SB. Polymorphic amplified typing sequences provide a novel approach to Escherichia coli O157:H7 strain typing. J. Clin. Microbiol. 2002 Apr; 40(4):1152-9.

  105. Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J. MAP kinase signalling cascade in Arabidopsis innate immunity. Nature 2002 Feb 28; 415(6875):977-83.

  106. Choi JY, Sifri CD, Goumnerov BC, Rahme LG, Ausubel FM, Calderwood SB. Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis. J. Bacteriol. 2002 Feb; 184(4):952-61.

  107. Aballay A, Ausubel FM. Caenorhabditis elegans as a host for the study of host-pathogen interactions. Curr. Opin. Microbiol. 2002 Feb; 5(1):97-101.

  108. 2001
  109. Hendrickson EL, Plotnikova J, Mahajan-Miklos S, Rahme LG, Ausubel FM. Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects, and mice. J. Bacteriol. 2001 Dec; 183(24):7126-34.

  110. Wildermuth MC, Dewdney J, Wu G, Ausubel FM. Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature 2001 Nov 29; 414(6863):562-5.

  111. Garsin DA, Sifri CD, Mylonakis E, Qin X, Singh KV, Murray BE, Calderwood SB, Ausubel FM. A simple model host for identifying Gram-positive virulence factors. Proc. Natl. Acad. Sci. U.S.A. 2001 Sep 11; 98(19):10892-7.

  112. Yorgey P, Rahme LG, Tan MW, Ausubel FM. The roles of mucD and alginate in the virulence of Pseudomonas aeruginosa in plants, nematodes and mice. Mol. Microbiol. 2001 Sep; 41(5):1063-76.

  113. Jander G, Cui J, Nhan B, Pierce NE, Ausubel FM. The TASTY locus on chromosome 1 of Arabidopsis affects feeding of the insect herbivore Trichoplusia ni. Plant Physiol. 2001 Jun; 126(2):890-8.

  114. Aballay A, Ausubel FM. Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc. Natl. Acad. Sci. U.S.A. 2001 Feb 27; 98(5):2735-9.

  115. 2000
  116. Ausubel FM. Arabidopsis genome. A milestone in plant biology. Plant Physiol. 2000 Dec; 124(4):1451-4.

  117. Drenkard E, Richter BG, Rozen S, Stutius LM, Angell NA, Mindrinos M, Cho RJ, Oefner PJ, Davis RW, Ausubel FM. A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis. Plant Physiol. 2000 Dec; 124(4):1483-92.

  118. Plotnikova JM, Rahme LG, Ausubel FM. Pathogenesis of the human opportunistic pathogen Pseudomonas aeruginosa PA14 in Arabidopsis. Plant Physiol. 2000 Dec; 124(4):1766-74.

  119. Tao Y, Yuan F, Leister RT, Ausubel FM, Katagiri F. Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2. Plant Cell 2000 Dec; 12(12):2541-2554.

  120. Aballay A, Yorgey P, Ausubel FM. Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr. Biol. 2000 Nov 30; 10(23):1539-42.

  121. Clarke JD, Volko SM, Ledford H, Ausubel FM, Dong X. Roles of salicylic acid, jasmonic acid, and ethylene in cpr-induced resistance in arabidopsis. Plant Cell 2000 Nov; 12(11):2175-90.

  122. Stone JM, Heard JE, Asai T, Ausubel FM. Simulation of fungal-mediated cell death by fumonisin B1 and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants. Plant Cell 2000 Oct; 12(10):1811-22.

  123. Asai T, Stone JM, Heard JE, Kovtun Y, Yorgey P, Sheen J, Ausubel FM. Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. Plant Cell 2000 Oct; 12(10):1823-36.

  124. Dewdney J, Reuber TL, Wildermuth MC, Devoto A, Cui J, Stutius LM, Drummond EP, Ausubel FM. Three unique mutants of Arabidopsis identify eds loci required for limiting growth of a biotrophic fungal pathogen. Plant J. 2000 Oct; 24(2):205-18.

  125. Ilag LL, Yadav RC, Huang N, Ronald PC, Ausubel FM. Isolation and characterization of disease resistance gene homologues from rice cultivar IR64. Gene 2000 Sep 19; 255(2):245-55.

  126. Mahajan-Miklos S, Rahme LG, Ausubel FM. Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts. Mol. Microbiol. 2000 Sep; 37(5):981-8.

  127. Keen N, Staskawicz B, Mekalanos J, Ausubel F, Cook RJ. Pathogens and hosts: the dance is the same, the couples are different. Proc. Natl. Acad. Sci. U.S.A. 2000 Aug 1; 97(16):8752-3.

  128. Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG. Plants and animals share functionally common bacterial virulence factors. Proc. Natl. Acad. Sci. U.S.A. 2000 Aug 1; 97(16):8815-21.

  129. Jander G, Rahme LG, Ausubel FM. Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects. J. Bacteriol. 2000 Jul; 182(13):3843-5.

  130. Hendrickson EL, Guevera P, Ausubel FM. The alternative sigma factor RpoN is required for hrp activity in Pseudomonas syringae pv. maculicola and acts at the level of hrpL transcription. J. Bacteriol. 2000 Jun; 182(12):3508-16.

  131. Hendrickson EL, Guevera P, Peñaloza-Vàzquez A, Shao J, Bender C, Ausubel FM. Virulence of the phytopathogen Pseudomonas syringae pv. maculicola is rpoN dependent. J. Bacteriol. 2000 Jun; 182(12):3498-507.

  132. Tan MW, Ausubel FM. Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis. Curr. Opin. Microbiol. 2000 Feb; 3(1):29-34.

  133. 1999
  134. Jirage D, Tootle TL, Reuber TL, Frost LN, Feys BJ, Parker JE, Ausubel FM, Glazebrook J. Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling. Proc. Natl. Acad. Sci. U.S.A. 1999 Nov 9; 96(23):13583-8.

  135. Cho RJ, Mindrinos M, Richards DR, Sapolsky RJ, Anderson M, Drenkard E, Dewdney J, Reuber TL, Stammers M, Federspiel N, Theologis A, Yang WH, Hubbell E, Au M, Chung EY, Lashkari D, Lemieux B, Dean C, Lipshutz RJ, Ausubel FM, Davis RW, Oefner PJ. Genome-wide mapping with biallelic markers in Arabidopsis thaliana. Nat. Genet. 1999 Oct; 23(2):203-7.

  136. Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM. Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc. Natl. Acad. Sci. U.S.A. 1999 Mar 2; 96(5):2408-13.

  137. Tan MW, Mahajan-Miklos S, Ausubel FM. Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc. Natl. Acad. Sci. U.S.A. 1999 Jan 19; 96(2):715-20.

  138. Mahajan-Miklos S, Tan MW, Rahme LG, Ausubel FM. Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell 1999 Jan 8; 96(1):47-56.

  139. 1998
  140. Wong SM, Carroll PA, Rahme LG, Ausubel FM, Calderwood SB. Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators. Infect. Immun. 1998 Dec; 66(12):5854-61.

  141. Reuber TL, Plotnikova JM, Dewdney J, Rogers EE, Wood W, Ausubel FM. Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants. Plant J. 1998 Nov; 16(4):473-85.

  142. Volko SM, Boller T, Ausubel FM. Isolation of new Arabidopsis mutants with enhanced disease susceptibility to Pseudomonas syringae by direct screening. Genetics 1998 Jun; 149(2):537-48.

  143. Kubasek WL, Ausubel FM, Shirley BW. A light-independent developmental mechanism potentiates flavonoid gene expression in Arabidopsis seedlings. Plant Mol. Biol. 1998 May; 37(2):217-23.

  144. Glazebrook J, Drenkard E, Preuss D, Ausubel FM. Use of cleaved amplified polymorphic sequences (CAPS) as genetic markers in Arabidopsis thaliana. Methods Mol. Biol. 1998; 82:173-82.

  145. Pegues DA, Colby C, Hibberd PL, Cohen LG, Ausubel FM, Calderwood SB, Hooper DC. The epidemiology of resistance to ofloxacin and oxacillin among clinical coagulase-negative staphylococcal isolates: analysis of risk factors and strain types. Clin. Infect. Dis. 1998 Jan; 26(1):72-9.

  146. 1997
  147. Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM. Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc. Natl. Acad. Sci. U.S.A. 1997 Nov 25; 94(24):13245-50.

  148. Li J, Kasper DL, Ausubel FM, Rosner B, Michel JL. Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus. Proc. Natl. Acad. Sci. U.S.A. 1997 Nov 25; 94(24):13251-6.

  149. Glazebrook J, Zook M, Mert F, Kagan I, Rogers EE, Crute IR, Holub EB, Hammerschmidt R, Ausubel FM. Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance. Genetics 1997 May; 146(1):381-92.

  150. Rogers EE, Ausubel FM. Arabidopsis enhanced disease susceptibility mutants exhibit enhanced susceptibility to several bacterial pathogens and alterations in PR-1 gene expression. Plant Cell 1997 Mar; 9(3):305-16.

  151. Glazebrook J, Rogers EE, Ausubel FM. Use of Arabidopsis for genetic dissection of plant defense responses. Annu. Rev. Genet. 1997; 31:547-69.

  152. 1996
  153. Leister RT, Ausubel FM, Katagiri F. Molecular recognition of pathogen attack occurs inside of plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1. Proc. Natl. Acad. Sci. U.S.A. 1996 Dec 24; 93(26):15497-502.

  154. Rogers EE, Glazebrook J, Ausubel FM. Mode of action of the Arabidopsis thaliana phytoalexin camalexin and its role in Arabidopsis-pathogen interactions. Mol. Plant Microbe Interact. 1996 Nov; 9(8):748-57.

  155. Calderwood SB, Baker MA, Carroll PA, Michel JL, Arbeit RD, Ausubel FM. Use of cleaved amplified polymorphic sequences to distinguish strains of Staphylococcus epidermidis. J. Clin. Microbiol. 1996 Nov; 34(11):2860-5.

  156. Glazebrook J, Rogers EE, Ausubel FM. Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening. Genetics 1996 Jun; 143(2):973-82.

  157. Reuber TL, Ausubel FM. Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes. Plant Cell 1996 Feb; 8(2):241-9.

  158. 1995
  159. Shirley BW, Kubasek WL, Storz G, Bruggemann E, Koornneef M, Ausubel FM, Goodman HM. Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis. Plant J. 1995 Nov; 8(5):659-71.

  160. Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM. Common virulence factors for bacterial pathogenicity in plants and animals. Science 1995 Jun 30; 268(5219):1899-902.

  161. Ausubel FM, Katagiri F, Mindrinos M, Glazebrook J. Use of Arabidopsis thaliana defense-related mutants to dissect the plant response to pathogens. Proc. Natl. Acad. Sci. U.S.A. 1995 May 9; 92(10):4189-96.

  162. Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD. Molecular genetics of plant disease resistance. Science 1995 May 5; 268(5211):661-7.

  163. Reuber TL, Ausubel FM. Differential mRNA display. Methods Cell Biol. 1995; 49:431-40.

  164. 1994
  165. Hanfstingl U, Berry A, Kellogg EA, Costa JT, Rüdiger W, Ausubel FM. Haplotypic divergence coupled with lack of diversity at the Arabidopsis thaliana alcohol dehydrogenase locus: roles for both balancing and directional selection? Genetics 1994 Nov; 138(3):811-28.

  166. Mindrinos M, Katagiri F, Yu GL, Ausubel FM. The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell 1994 Sep 23; 78(6):1089-99.

  167. Glazebrook J, Ausubel FM. Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens. Proc. Natl. Acad. Sci. U.S.A. 1994 Sep 13; 91(19):8955-9.

  168. Greenberg JT, Guo A, Klessig DF, Ausubel FM. Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions. Cell 1994 May 20; 77(4):551-63.

  169. 1993
  170. Susek RE, Ausubel FM, Chory J. Signal transduction mutants of Arabidopsis uncouple nuclear CAB and RBCS gene expression from chloroplast development. Cell 1993 Sep 10; 74(5):787-99.

  171. Greenberg JT, Ausubel FM. Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging. Plant J. 1993 Aug; 4(2):327-41.

  172. Konieczny A, Ausubel FM. A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers. Plant J. 1993 Aug; 4(2):403-10.

  173. Yu GL, Katagiri F, Ausubel FM. Arabidopsis mutations at the RPS2 locus result in loss of resistance to Pseudomonas syringae strains expressing the avirulence gene avrRpt2. Mol. Plant Microbe Interact. ; 6(4):434-43.

  174. Melan MA, Dong X, Endara ME, Davis KR, Ausubel FM, Peterman TK. An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate. Plant Physiol. 1993 Feb; 101(2):441-50.

  175. 1992
  176. Michel JL, Madoff LC, Olson K, Kling DE, Kasper DL, Ausubel FM. Large, identical, tandem repeating units in the C protein alpha antigen gene, bca, of group B streptococci. Proc. Natl. Acad. Sci. U.S.A. 1992 Nov 1; 89(21):10060-4.

  177. Kubasek WL, Shirley BW, McKillop A, Goodman HM, Briggs W, Ausubel FM. Regulation of Flavonoid Biosynthetic Genes in Germinating Arabidopsis Seedlings. Plant Cell 1992 Oct; 4(10):1229-1236.

  178. Voytas DF, Cummings MP, Koniczny A, Ausubel FM, Rodermel SR. copia-like retrotransposons are ubiquitous among plants. Proc. Natl. Acad. Sci. U.S.A. 1992 Aug 1; 89(15):7124-8.

  179. Huala E, Stigter J, Ausubel FM. The central domain of Rhizobium leguminosarum DctD functions independently to activate transcription. J. Bacteriol. 1992 Feb; 174(4):1428-31.

  180. Sun T, Goodman HM, Ausubel FM. Cloning the Arabidopsis GA1 Locus by Genomic Subtraction. Plant Cell 1992 Feb; 4(2):119-128.

  181. 1991
  182. Dickstein R, Scheirer DC, Fowle WH, Ausubel FM. Nodules elicited by Rhizobium meliloti heme mutants are arrested at an early stage of development. Mol. Gen. Genet. 1991 Dec; 230(3):423-32.

  183. Keith B, Dong XN, Ausubel FM, Fink GR. Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. Proc. Natl. Acad. Sci. U.S.A. 1991 Oct 1; 88(19):8821-5.

  184. Richards EJ, Goodman HM, Ausubel FM. The centromere region of Arabidopsis thaliana chromosome 1 contains telomere-similar sequences. Nucleic Acids Res. 1991 Jun 25; 19(12):3351-7.

  185. Michel JL, Madoff LC, Kling DE, Kasper DL, Ausubel FM. Cloned alpha and beta C-protein antigens of group B streptococci elicit protective immunity. Infect. Immun. 1991 Jun; 59(6):2023-8.

  186. Feinbaum RL, Storz G, Ausubel FM. High intensity and blue light regulated expression of chimeric chalcone synthase genes in transgenic Arabidopsis thaliana plants. Mol. Gen. Genet. 1991 May; 226(3):449-56.

  187. Konieczny A, Voytas DF, Cummings MP, Ausubel FM. A superfamily of Arabidopsis thaliana retrotransposons. Genetics 1991 Apr; 127(4):801-9.

  188. Dong X, Mindrinos M, Davis KR, Ausubel FM. Induction of Arabidopsis defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene. Plant Cell 1991 Jan; 3(1):61-72.

  189. Huala E, Moon AL, Ausubel FM. Aerobic inactivation of Rhizobium meliloti NifA in Escherichia coli is mediated by lon and two newly identified genes, snoB and snoC. J. Bacteriol. 1991 Jan; 173(1):382-90.

  190. 1990
  191. Voytas DF, Konieczny A, Cummings MP, Ausubel FM. The structure, distribution and evolution of the Ta1 retrotransposable element family of Arabidopsis thaliana. Genetics 1990 Nov; 126(3):713-21.

  192. Straus D, Ausubel FM. Genomic subtraction for cloning DNA corresponding to deletion mutations. Proc. Natl. Acad. Sci. U.S.A. 1990 Mar; 87(5):1889-93.

  193. Honma MA, Asomaning M, Ausubel FM. Rhizobium meliloti nodD genes mediate host-specific activation of nodABC. J. Bacteriol. 1990 Feb; 172(2):901-11.

  194. 1989
  195. Chory J, Peto C, Feinbaum R, Pratt L, Ausubel F. Arabidopsis thaliana mutant that develops as a light-grown plant in the absence of light. Cell 1989 Sep 8; 58(5):991-9.

  196. Bloch CA, Thorne GM, Ausubel FM. General method for site-directed mutagenesis in Escherichia coli O18ac:K1:H7: deletion of the inducible superoxide dismutase gene, sodA, does not diminish bacteremia in neonatal rats. Infect. Immun. 1989 Jul; 57(7):2141-8.

  197. Huala E, Ausubel FM. The central domain of Rhizobium meliloti NifA is sufficient to activate transcription from the R. meliloti nifH promoter. J. Bacteriol. 1989 Jun; 171(6):3354-65.

  198. Olszewski NE, Gast RT, Ausubel FM. A dual-labeling method for identifying differentially expressed genes: use in the identification of cDNA clones that hybridize to RNAs whose abundance in tomato flowers is potentially regulated by gibberellins. Gene 1989 Apr 15; 77(1):155-62.

  199. Albright LM, Ronson CW, Nixon BT, Ausubel FM. Identification of a gene linked to Rhizobium meliloti ntrA whose product is homologous to a family to ATP-binding proteins. J. Bacteriol. 1989 Apr; 171(4):1932-41.

  200. de Bruijn FJ, Rossbach S, Schneider M, Ratet P, Messmer S, Szeto WW, Ausubel FM, Schell J. Rhizobium meliloti 1021 has three differentially regulated loci involved in glutamine biosynthesis, none of which is essential for symbiotic nitrogen fixation. J. Bacteriol. 1989 Mar; 171(3):1673-82.

  201. Albright LM, Huala E, Ausubel FM. Prokaryotic signal transduction mediated by sensor and regulator protein pairs. Annu. Rev. Genet. 1989; 23:311-36.

  202. 1988
  203. Debellé F, Maillet F, Vasse J, Rosenberg C, de Billy F, Truchet G, Dénarié J, Ausubel FM. Interference between Rhizobium meliloti and Rhizobium trifolii nodulation genes: genetic basis of R. meliloti dominance. J. Bacteriol. 1988 Dec; 170(12):5718-27.

  204. Olszewski NE, Martin FB, Ausubel FM. Specialized binary vector for plant transformation: expression of the Arabidopsis thaliana AHAS gene in Nicotiana tabacum. Nucleic Acids Res. 1988 Nov 25; 16(22):10765-82.

  205. Voytas DF, Ausubel FM. A copia-like transposable element family in Arabidopsis thaliana. Nature 1988 Nov 17; 336(6196):242-4.

  206. Dickstein R, Bisseling T, Reinhold VN, Ausubel FM. Expression of nodule-specific genes in alfalfa root nodules blocked at an early stage of development. Genes Dev. 1988 Jun; 2(6):677-87.

  207. Feinbaum RL, Ausubel FM. Transcriptional regulation of the Arabidopsis thaliana chalcone synthase gene. Mol. Cell. Biol. 1988 May; 8(5):1985-92.

  208. Richards EJ, Ausubel FM. Isolation of a higher eukaryotic telomere from Arabidopsis thaliana. Cell 1988 Apr 8; 53(1):127-36.

  209. Dunn K, Dickstein R, Feinbaum R, Burnett BK, Peterman TK, Thoidis G, Goodman HM, Ausubel FM. Developmental regulation of nodule-specific genes in alfalfa root nodules. Mol. Plant Microbe Interact. 1988 Feb; 1(2):66-74.

  210. 1987
  211. Honma MA, Ausubel FM. Rhizobium meliloti has three functional copies of the nodD symbiotic regulatory gene. Proc. Natl. Acad. Sci. U.S.A. 1987 Dec; 84(23):8558-62.

  212. Ronson CW, Astwood PM, Nixon BT, Ausubel FM. Deduced products of C4-dicarboxylate transport regulatory genes of Rhizobium leguminosarum are homologous to nitrogen regulatory gene products. Nucleic Acids Res. 1987 Oct 12; 15(19):7921-34.

  213. Ronson CW, Nixon BT, Ausubel FM. Conserved domains in bacterial regulatory proteins that respond to environmental stimuli. Cell 1987 Jun 5; 49(5):579-81.

  214. Ronson CW, Nixon BT, Albright LM, Ausubel FM. Rhizobium meliloti ntrA (rpoN) gene is required for diverse metabolic functions. J. Bacteriol. 1987 Jun; 169(6):2424-31.

  215. Wilson KJ, Anjaiah V, Nambiar PT, Ausubel FM. Isolation and characterization of symbiotic mutants of bradyrhizobium sp. (Arachis) strain NC92: mutants with host-specific defects in nodulation and nitrogen fixation. J. Bacteriol. 1987 May; 169(5):2177-86.

  216. Szeto WW, Nixon BT, Ronson CW, Ausubel FM. Identification and characterization of the Rhizobium meliloti ntrC gene: R. meliloti has separate regulatory pathways for activation of nitrogen fixation genes in free-living and symbiotic cells. J. Bacteriol. 1987 Apr; 169(4):1423-32.

  217. Buikema WJ, Klingensmith JA, Gibbons SL, Ausubel FM. Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes. J. Bacteriol. 1987 Mar; 169(3):1120-6.

  218. Earl CD, Ronson CW, Ausubel FM. Genetic and structural analysis of the Rhizobium meliloti fixA, fixB, fixC, and fixX genes. J. Bacteriol. 1987 Mar; 169(3):1127-36.

  219. Marvel DJ, Torrey JG, Ausubel FM. Rhizobium symbiotic genes required for nodulation of legume and nonlegume hosts. Proc. Natl. Acad. Sci. U.S.A. 1987 Mar; 84(5):1319-23.

  220. Chory J, Voytas DF, Olszewski NE, Ausubel FM. Gibberellin-Induced Changes in the Populations of Translatable mRNAs and Accumulated Polypeptides in Dwarfs of Maize and Pea. Plant Physiol. 1987 Jan; 83(1):15-23.

  221. 1986
  222. Bloch CA, Ausubel FM. Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA. J. Bacteriol. 1986 Nov; 168(2):795-8.

  223. Nixon BT, Ronson CW, Ausubel FM. Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genes ntrB and ntrC. Proc. Natl. Acad. Sci. U.S.A. 1986 Oct; 83(20):7850-4.

  224. Ausubel FM. Biological nitrogen fixation: recent advances and future prospects. Regul. Toxicol. Pharmacol. 1986 Mar; 6(1):1-10.

  225. Gussin GN, Ronson CW, Ausubel FM. Regulation of nitrogen fixation genes. Annu. Rev. Genet. 1986; 20:567-91.

  226. 1985
  227. Marvel DJ, Kuldau G, Hirsch A, Richards E, Torrey JG, Ausubel FM. Conservation of nodulation genes between Rhizobium meliloti and a slow-growing Rhizobium strain that nodulates a nonlegume host. Proc. Natl. Acad. Sci. U.S.A. 1985 Sep; 82(17):5841-5.

  228. Buikema WJ, Szeto WW, Lemley PV, Orme-Johnson WH, Ausubel FM. Nitrogen fixation specific regulatory genes of Klebsiella pneumoniae and Rhizobium meliloti share homology with the general nitrogen regulatory gene ntrC of K. pneumoniae. Nucleic Acids Res. 1985 Jun 25; 13(12):4539-55.

  229. Lang-Unnasch N, Ausubel FM. Nodule-specific polypeptides from effective alfalfa root nodules and from ineffective nodules lacking nitrogenase. Plant Physiol. 1985 Apr; 77(4):833-9.

  230. Lang-Unnasch N, Dunn K, Ausubel FM. Symbiotic nitrogen fixation: developmental genetics of nodule formation. Cold Spring Harb. Symp. Quant. Biol. 1985; 50:555-63.

  231. 1984
  232. Hirsch AM, Wilson KJ, Jones JD, Bang M, Walker VV, Ausubel FM. Rhizobium meliloti nodulation genes allow Agrobacterium tumefaciens and Escherichia coli to form pseudonodules on alfalfa. J. Bacteriol. 1984 Jun; 158(3):1133-43.

  233. Ausubel FM. Regulation of nitrogen fixation genes. Cell 1984 May; 37(1):5-6.

  234. Szeto WW, Zimmerman JL, Sundaresan V, Ausubel FM. A Rhizobium meliloti symbiotic regulatory gene. Cell 1984 Apr; 36(4):1035-43.

  235. Brown SE, Ausubel FM. Mutations affecting regulation of the Klebsiella pneumoniae nifH (nitrogenase reductase) promotor. J. Bacteriol. 1984 Jan; 157(1):143-7.

  236. 1983
  237. Zimmerman JL, Szeto WW, Ausubel FM. Molecular characterization of Tn5-induced symbiotic (Fix-) mutants of Rhizobium meliloti. J. Bacteriol. 1983 Dec; 156(3):1025-34.

  238. Ow DW, Ausubel FM. Conditionally replicating plasmid vectors that can integrate into the Klebsiella pneumoniae chromosome via bacteriophage P4 site-specific recombination. J. Bacteriol. 1983 Aug; 155(2):704-13.

  239. Sundaresan V, Ow DW, Ausubel FM. Activation of Klebsiella pneumoniae and Rhizobium meliloti nitrogenase promoters by gln (ntr) regulatory proteins. Proc. Natl. Acad. Sci. U.S.A. 1983 Jul; 80(13):4030-4.

  240. Hirsch AM, Bang M, Ausubel FM. Ultrastructural analysis of ineffective alfalfa nodules formed by nif::Tn5 mutants of Rhizobium meliloti. J. Bacteriol. 1983 Jul; 155(1):367-80.

  241. Ow DW, Sundaresan V, Rothstein DM, Brown SE, Ausubel FM. Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region. Proc. Natl. Acad. Sci. U.S.A. 1983 May; 80(9):2524-8.

  242. Sundaresan V, Jones JD, Ow DW, Ausubel FM. Klebsiella pneumoniae nifA product activates the Rhizobium meliloti nitrogenase promoter. Nature 1983 Feb 24; 301(5902):728-32.

  243. Ow DW, Ausubel FM. Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae. Nature 1983 Jan 27; 301(5898):307-13.

  244. Riedel GE, Brown SE, Ausubel FM. Nitrogen fixation by Klebsiella pneumoniae is inhibited by certain multicopy hybrid nif plasmids. J. Bacteriol. 1983 Jan; 153(1):45-56.

  245. Earl CD, Ausubel FM. The genetic engineering of nitrogen fixation. Nutr. Rev. 1983 Jan; 41(1):1-6.

  246. de Bruijn FJ, Stroke IL, Marvel DJ, Ausubel FM. Construction of a correlated physical and genetic map of the Klebsiella pneumoniae hisDGO region using transposon Tn5 mutagenesis. EMBO J. 1983; 2(10):1831-8.

  247. Buikema WJ, Long SR, Brown SE, van den Bos RC, Earl C, Ausubel FM. Physical and genetic characterization of Rhizobium meliloti symbiotic mutants. J. Mol. Appl. Genet. 1983; 2(3):249-60.

  248. 1982
  249. Hirsch AM, Long SR, Bang M, Haskins N, Ausubel FM. Structural studies of alfalfa roots infected with nodulation mutants of Rhizobium meliloti. J. Bacteriol. 1982 Jul; 151(1):411-9.

  250. Ruvkun GB, Sundaresan V, Ausubel FM. Directed transposon Tn5 mutagenesis and complementation analysis of Rhizobium meliloti symbiotic nitrogen fixation genes. Cell 1982 Jun; 29(2):551-9.

  251. Ruvkun GB, Sundaresan V, Ausubel FM. Specific protection of nucleotides in the lac operator from DMS methylation and DNase I nicking by crude bacterial cell extracts. Gene 1982 Jun; 18(3):247-55.

  252. Friedman AM, Long SR, Brown SE, Buikema WJ, Ausubel FM. Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants. Gene 1982 Jun; 18(3):289-96.

  253. Ausubel FM. Molecular genetics of symbiotic nitrogen fixation. Cell 1982 May; 29(1):1-2.

  254. Meade HM, Long SR, Ruvkun GB, Brown SE, Ausubel FM. Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis. J. Bacteriol. 1982 Jan; 149(1):114-22.

  255. Ruvkun GB, Long SR, Meade HM, van den Bos RC, Ausubel FM. ISRm1: A Rhizobium meliloti insertion sequence that transposes preferentially into nitrogen fixation genes. J. Mol. Appl. Genet. 1982; 1(5):405-18.

  256. 1981
  257. Sundaresan V, Ausubel FM. Nucleotide sequence of the gene coding for the nitrogenase iron protein from Klebsiella pneumoniae. J. Biol. Chem. 1981 Mar 25; 256(6):2808-12.

  258. Ausubel FM, Cannon FC. Molecular genetic analysis of Klebsiella pneumoniae nitrogen-fixation (nif) genes. Cold Spring Harb. Symp. Quant. Biol. 1981; 45 Pt 2:487-99.

  259. Ruvkun GB, Ausubel FM. A general method for site-directed mutagenesis in prokaryotes. Nature 1981 Jan 1; 289(5793):85-8.

  260. de Bruijn FJ, Ausubel FM. The cloning and transposon Tn5 mutagenesis of the glnA region of Klebsiella pneumoniae: identification of glnR, a gene involved in the regulation of the nif and hut operons. Mol. Gen. Genet. 1981; 183(2):289-97.

  261. 1980
  262. Ow DW, Ausubel FM. Recombinant P4 bacteriophages propagate as viable lytic phages or as autonomous plasmids in Klebsiella pneumoniae. Mol. Gen. Genet. 1980; 180(1):165-75.

  263. Ruvkun GB, Ausubel FM. Interspecies homology of nitrogenase genes. Proc. Natl. Acad. Sci. U.S.A. 1980 Jan; 77(1):191-5.

  264. 1979
  265. Ausubel FM, Bird SC, Durbin KJ, Janssen KA, Margolskee RF, Peskin AP. Glutamine synthetase mutations which affect expression of nitrogen fixation genes in Klebsiella pneumoniae. J. Bacteriol. 1979 Nov; 140(2):597-606.

  266. Bedbrook JR, Lehrach H, Ausubel FM. Directive segregation in the basis of colE1 plasmid incompatibility. Nature 1979 Oct 11; 281(5731):447-52.

  267. Miller SS, Ausubel FM, Bogorad L. Cyanobacterial ribonucleic acid polymerases recognize lambda promoters. J. Bacteriol. 1979 Oct; 140(1):246-50.

  268. Cannon FC, Riedel GE, Ausubel FM. Overlapping sequences of Klebsiella pneumoniae nifDNA cloned and characterized. Mol. Gen. Genet. 1979 Jul 2; 174(1):59-66.

  269. Riedel GE, Ausubel FM, Cannon FC. Physical map of chromosomal nitrogen fixation (nif) genes of Klebsiella pneumoniae. Proc. Natl. Acad. Sci. U.S.A. 1979 Jun; 76(6):2866-70.

  270. Greer H, Ausubel FM. Radiochemical identification of the kil gene product of bacteriophage lambda. Virology 1979 Jun; 95(2):577-80.

  271. 1977
  272. Cannon FC, Riedel GE, Ausubel FM. Recombinant plasmid that carries part of the nitrogen fixation (nif) gene cluster of Klebsiella pneumoniae. Proc. Natl. Acad. Sci. U.S.A. 1977 Jul; 74(7):2963-7.

  273. Ausubel F, Riedel G, Cannon F, Peskin A, Margolskee R. Cloning nitrogen fixing genes from Klebsiella pneumoniae in vitro and the isolation of NIF promoter mutants affecting glutamine synthetase regulation. Basic Life Sci. 1977; 9:111-28.

  274. 1976
  275. Bedbrook JR, Ausubel FM. Recombination between bacterial plasmids leading to the formation of plasmid multimers. Cell 1976 Dec; 9(4 PT 2):707-16.

  276. 1974
  277. Streicher SL, Shanmugam KT, Ausubel F, Morandi C, Goldberg RB. Regulation of nitrogen fixation in Klebsiella pneumoniae: evidence for a role of glutamine synthetase as a regulator of nitrogenase synthesis. J. Bacteriol. 1974 Nov; 120(2):815-21.

  278. Ausubel F, Beckwith J, Janssen K. The politics of genetic engineering: who decides who's defective? Psychol Today 1974 Jun; 8(1):30+.

  279. Ausubel FM. Radiochemical purification of bacteriophage lambda integrase. Nature 1974 Jan 18; 247(437):152-4.

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