Denis Titov

Mootha Lab

Assistant Adjunct Professor

University of California- Berkeley


  1. Titov DV, Cracan V, Goodman RP, Peng J, Grabarek Z, Mootha VK. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science 2016 Apr 8; 352(6282):231-5.

  2. Lewis-Smith D, Kamer KJ, Griffin H, Childs AM, Pysden K, Titov D, Duff J, Pyle A, Taylor RW, Yu-Wai-Man P, Ramesh V, Horvath R, Mootha VK, Chinnery PF. Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood. Neurol Genet 2016 Apr; 2(2):e59.

  3. 2015
  4. He QL, Titov DV, Li J, Tan M, Ye Z, Zhao Y, Romo D, Liu JO. Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angew. Chem. Int. Ed. Engl. 2015 Feb 2; 54(6):1859-63.

  5. 2012
  6. Titov DV, Liu JO. Identification and validation of protein targets of bioactive small molecules. Bioorg. Med. Chem. 2012 Mar 15; 20(6):1902-9.

  7. 2011
  8. Titov DV, Gilman B, He QL, Bhat S, Low WK, Dang Y, Smeaton M, Demain AL, Miller PS, Kugel JF, Goodrich JA, Liu JO. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nat. Chem. Biol. 2011 Mar; 7(3):182-8.

  9. Liu JO, Titov DV, Dang Y, He Q. Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP. Mol. Cell 2011 Jan 21; 41(2):131-3.

  10. 2006
  11. Ni Q, Titov DV, Zhang J. Analyzing protein kinase dynamics in living cells with FRET reporters. Methods 2006 Nov; 40(3):279-86.

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