About Natalia Kirienko
I work in the Ausubel and Ruvkun labs, using C. elegans to study the conserved mechanisms of organismal defenses to stresses and infection with pathogens. In my spare time, I enjoy reading, hiking and swimming.
Publications- Pellegrino MW, Nargund AM, Kirienko NV, Gillis R, Fiorese CJ, Haynes CM. Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection. Nature 2014 Sep 28.
- Kuzmanov A, Karina EI, Kirienko NV, Fay DS. The conserved PBAF nucleosome-remodeling complex mediates the response to stress in Caenorhabditis elegans. Mol. Cell. Biol. 2014 Mar; 34(6):1121-35.
- Kirienko NV, Cezairliyan BO, Ausubel FM, Powell JR. Pseudomonas aeruginosa PA14 pathogenesis in Caenorhabditis elegans. Methods Mol. Biol. 2014; 1149:653-69.
- Conery AL, Larkins-Ford J, Ausubel FM, Kirienko NV. High-throughput screening for novel anti-infectives using a C. elegans pathogenesis model. Curr Protoc Chem Biol 2014; 6(1):25-37.
- Riedel CG, Dowen RH, Lourenco GF, Kirienko NV, Heimbucher T, West JA, Bowman SK, Kingston RE, Dillin A, Asara JM, Ruvkun G. DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nat. Cell Biol. 2013 May; 15(5):491-501.
- Kirienko NV, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM. Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death. Cell Host Microbe 2013 Apr 17; 13(4):406-16.
- Pukkila-Worley R, Feinbaum R, Kirienko NV, Larkins-Ford J, Conery AL, Ausubel FM. Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection. PLoS Genet. 2012 Jun; 8(6):e1002733.
- McEwan DL, Kirienko NV, Ausubel FM. Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans. Cell Host Microbe 2012 Apr 19; 11(4):364-74.
- Sait M, Kamneva OK, Fay DS, Kirienko NV, Polek J, Shirasu-Hiza MM, Ward NL. Genomic and Experimental Evidence Suggests that Verrucomicrobium spinosum Interacts with Eukaryotes. Front Microbiol 2011; 2:211.
- Kirienko NV, Mani K, Fay DS. Cancer models in Caenorhabditis elegans. Dev. Dyn. 2010 May; 239(5):1413-48.
- Kirienko NV, Fay DS. SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network. EMBO J. 2010 Feb 17; 29(4):727-39.
- Barends TR, Hartmann E, Griese JJ, Beitlich T, Kirienko NV, Ryjenkov DA, Reinstein J, Shoeman RL, Gomelsky M, Schlichting I. Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature 2009 Jun 18; 459(7249):1015-8.
- Kirienko NV, McEnerney JD, Fay DS. Coordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2. PLoS Genet. 2008 Apr; 4(4):e1000059.
- Kirienko NV, Fay DS. Transcriptome profiling of the C. elegans Rb ortholog reveals diverse developmental roles. Dev. Biol. 2007 May 15; 305(2):674-84.
- Bender AM, Kirienko NV, Olson SK, Esko JD, Fay DS. lin-35/Rb and the CoREST ortholog spr-1 coordinately regulate vulval morphogenesis and gonad development in C. elegans. Dev. Biol. 2007 Feb 15; 302(2):448-62.
- Kirienko NV, Lepikhov KA, Zheleznaya LA, Matvienko NI. Significance of codon usage and irregularities of rare codon distribution in genes for expression of BspLU11III methyltransferases. Biochemistry Mosc. 2004 May; 69(5):527-35.
2014
2013
2012
2011
2010
2009
2008
2007
2004