Justine Melo

Ruvkun Lab

Research Fellow

About Justine Melo

Interests: Appetite regulation and behavioral responses to physiologic stress. I am interested in physiologic stress: the ways in which environment imposes stress on an organism, how stress is sensed at a cellular level, and the mechanisms by which stress signals are relayed to the nervous system to produce a highly adaptive dispersal behavior.

  1. Melo JA, Ruvkun G. Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses. Cell 2012 Apr 13; 149(2):452-66.

  2. 2009
  3. Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 2009 Feb 15; 23(4):496-511.

  4. 2008
  5. Bonilla CY, Melo JA, Toczyski DP. Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol. Cell 2008 May 9; 30(3):267-76.

  6. 2004
  7. Kaye JA, Melo JA, Cheung SK, Vaze MB, Haber JE, Toczyski DP. DNA breaks promote genomic instability by impeding proper chromosome segregation. Curr. Biol. 2004 Dec 14; 14(23):2096-106.

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