Stefan Pinter

Lee Lab

Assistant Professor

Department of Genetics and Genome Sciences, UConn Health


About Stefan Pinter

I obtained my PhD in Molecular Biology from Princeton University where I studied helicase function in nuclear and mitochondrial DNA replication and repair. In Dr. Jeannie Lee's lab, I am primarily interested in using genomic tools to examine how sequence context directs trans-acting factors in specifying chromatin states over large chromosomal domains. What role do non-coding RNAs play in this process and can we link specific factors to regulation of somatic or germline development?

  1. Pinter SF, Sadreyev RI, Yildirim E, Jeon Y, Ohsumi TK, Borowsky M, Lee JT. Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. Genome Res. 2012 Oct; 22(10):1864-76.

  2. Yildirim E, Sadreyev RI, Pinter SF, Lee JT. X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription. Nat. Struct. Mol. Biol. 2012 Jan; 19(1):56-61.

  3. 2011
  4. Spencer RJ, del Rosario BC, Pinter SF, Lessing D, Sadreyev RI, Lee JT. A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation. Genetics 2011 Oct; 189(2):441-54.

  5. 2009
  6. Donohoe ME, Silva SS, Pinter SF, Xu N, Lee JT. The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature 2009 Jul 2; 460(7251):128-32.

  7. 2008
  8. Pinter SF, Aubert SD, Zakian VA. The Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA. Mol. Cell. Biol. 2008 Nov; 28(21):6594-608.

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