Sascha Russel

Ruvkun Lab

Undergraduate teaching fellow, Harvard University

About Sascha Russel

Interests: Developmental Biology, Genetics, Mechanical Machines, Bugs, Food, Education and People! As a model of a complex developmental program I investigate how C. elegans determines when to molt and when not to. I am also interested in how the when of molting is coordinated with the how across different tissues and in different environmental contexts. This worm usually molts four times during its development and then stops once it reaches sexual maturity; some components of the molting cycle and machinery are conserved amongst the four molts, and some are unique. I have identified a novel heterochronic gene that is required both for the completion of a molt as well as their cessation in adults; significantly it is highly conserved in humans.