James Toombs

Blower Lab

Research Program Manager

Brigham and Women's Hospital


  1. Toombs JA, Petri M, Paul KR, Kan GY, Ben-Hur A, Ross ED. De novo design of synthetic prion domains. Proc. Natl. Acad. Sci. U.S.A. 2012 Apr 24; 109(17):6519-24.

  2. 2011
  3. Toombs JA, Liss NM, Cobble KR, Ben-Musa Z, Ross ED. [PSI+] maintenance is dependent on the composition, not primary sequence, of the oligopeptide repeat domain. PLoS ONE 2011; 6(7):e21953.

  4. 2010
  5. Ross ED, Toombs JA. The effects of amino acid composition on yeast prion formation and prion domain interactions. Prion ; 4(2):60-5.

  6. Toombs JA, McCarty BR, Ross ED. Compositional determinants of prion formation in yeast. Mol. Cell. Biol. 2010 Jan; 30(1):319-32.

  7. 2009
  8. McBryant SJ, Klonoski J, Sorensen TC, Norskog SS, Williams S, Resch MG, Toombs JA, Hobdey SE, Hansen JC. Determinants of histone H4 N-terminal domain function during nucleosomal array oligomerization: roles of amino acid sequence, domain length, and charge density. J. Biol. Chem. 2009 Jun 19; 284(25):16716-22.

  9. 2006
  10. Brachmann A, Toombs JA, Ross ED. Reporter assay systems for [URE3] detection and analysis. Methods 2006 May; 39(1):35-42.

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