Jesse Cochrane

Kingston Lab

Research Associate

Department of Molecular Biology
Simches Research Center
185 Cambridge Street, CPZN7250
Boston, MA 02114


  1. Cajigas I, Leib DE, Cochrane J, Luo H, Swyter KR, Chen S, Clark BS, Thompson J, Yates JR, Kingston RE, Kohtz JD. Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling. Development 2015 Aug 1; 142(15):2641-52.

  2. 2011
  3. Iwase S, Xiang B, Ghosh S, Ren T, Lewis PW, Cochrane JC, Allis CD, Picketts DJ, Patel DJ, Li H, Shi Y. ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat. Struct. Mol. Biol. 2011 Jul; 18(7):769-76.

  4. 2010
  5. Antonioli AH, Cochrane JC, Lipchock SV, Strobel SA. Plasticity of the RNA kink turn structural motif. RNA 2010 Apr; 16(4):762-8.

  6. 2009
  7. Cochrane JC, Lipchock SV, Smith KD, Strobel SA. Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme. Biochemistry 2009 Apr 21; 48(15):3239-46.

  8. 2008
  9. Cochrane JC, Strobel SA. Catalytic strategies of self-cleaving ribozymes. Acc. Chem. Res. 2008 Aug; 41(8):1027-35.

  10. Cochrane JC, Strobel SA. Riboswitch effectors as protein enzyme cofactors. RNA 2008 Jun; 14(6):993-1002.

  11. 2007
  12. Strobel SA, Cochrane JC. RNA catalysis: ribozymes, ribosomes, and riboswitches. Curr Opin Chem Biol 2007 Dec; 11(6):636-43.

  13. Cochrane JC, Lipchock SV, Strobel SA. Structural investigation of the GlmS ribozyme bound to Its catalytic cofactor. Chem. Biol. 2007 Jan; 14(1):97-105.

  14. 2005
  15. Tabtiang RK, Cezairliyan BO, Grant RA, Cochrane JC, Sauer RT. Consolidating critical binding determinants by noncyclic rearrangement of protein secondary structure. Proc. Natl. Acad. Sci. U.S.A. 2005 Feb 15; 102(7):2305-9.

  16. 2004
  17. Cochrane JC, Strobel SA. Probing RNA structure and function by nucleotide analog interference mapping. Curr Protoc Nucleic Acid Chem 2004 Sep; Chapter 6:Unit 6.9.

  18. 2003
  19. Cochrane JC, Batey RT, Strobel SA. Quantitation of free energy profiles in RNA-ligand interactions by nucleotide analog interference mapping. RNA 2003 Oct; 9(10):1282-9.

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