Behfar Ardehali

Kingston Lab

Research Fellow

Department of Molecular Biology
Simches Research Center
185 Cambridge Street, CPZN7250
Boston, MA 02114


About Behfar Ardehali

I received my B.Sc. in general biology from Shiraz University in Shiraz, Iran, and I obtained my Ph.D. in genetics from Cornell University in Ithaca, NY. I joined the Kingston Lab in the February of 2011 as a research fellow. Polycomb repressive complexes are required for proper development of multicellular organisms by facilitating silencing of a wide array of developmentally-regulated genes in a tightly-controlled spatial and temporal manner. I am interested in examining the mechanistic roles of polycomb repressive complexes in various biological processes.

  1. Ardehali MB, Anselmo A, Cochrane JC, Kundu S, Sadreyev RI, Kingston RE. Polycomb Repressive Complex 2 Methylates Elongin A to Regulate Transcription. Mol. Cell 2017 Dec 07; 68(5):872-884.e6.

  2. 2011
  3. Ardehali MB, Mei A, Zobeck KL, Caron M, Lis JT, Kusch T. Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription. EMBO J. 2011 Jul 20; 30(14):2817-28.

  4. 2009
  5. Ardehali MB, Lis JT. Tracking rates of transcription and splicing in vivo. Nat. Struct. Mol. Biol. 2009 Nov; 16(11):1123-4.

  6. Fuda NJ, Ardehali MB, Lis JT. Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 2009 Sep 10; 461(7261):186-92.

  7. Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT. Spt6 enhances the elongation rate of RNA polymerase II in vivo. EMBO J. 2009 Apr 22; 28(8):1067-77.

  8. 2007
  9. Yao J, Ardehali MB, Fecko CJ, Webb WW, Lis JT. Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation. Mol. Cell 2007 Dec 28; 28(6):978-90.

  10. 2006
  11. Adelman K, Wei W, Ardehali MB, Werner J, Zhu B, Reinberg D, Lis JT. Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Mol. Cell. Biol. 2006 Jan; 26(1):250-60.

Back to top