Subramanian Lab

Radhika Subramanian, Ph.D.

Department of Molecular Biology
Simches Research Center
Boston, MA 02114


  1. Mani N, Jiang S, Subramanian R. Differential Regulation of Single Microtubules and Cross-linked Bundles by a Minimal Three-Protein Module. bioRxiv, 2020 March.

  2. 2019
  3. Jiang S, Mani N, Wilson-Kubalek EM, Ku PI, Milligan RA, Subramanian R. Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. Dev. Cell 2019 Jun 03; 49(5):711-730.e8.

  4. 2018
  5. Wijeratne S, Subramanian R. Geometry of antiparallel microtubule bundles regulates relative sliding and stalling by PRC1 and Kif4A. Elife 2018 10 24; 7

  6. 2015
  7. Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, Hideshima T, Majireck MM, Hussain MM, Singh S, Quiroz R, Iaconelli J, Karmacharya R, Tolliday NJ, Clemons PA, Moore MAS, Stern AM, Shamji AF, Ebert BL, Golub TR, Raje NS, Scadden DT, Schreiber SL. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. Cell Rep 2015 Feb 10; 10(5):755-770.

  8. 2014
  9. He M, Subramanian R, Bangs F, Omelchenko T, Liem KF, Kapoor TM, Anderson KV. The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment. Nat. Cell Biol. 2014 Jul; 16(7):663-72.

  10. 2013
  11. Subramanian R, Kapoor TM. Slipping past the spindle assembly checkpoint. Nat. Cell Biol. 2013 Nov; 15(11):1261-3.

  12. Subramanian R, Ti SC, Tan L, Darst SA, Kapoor TM. Marking and measuring single microtubules by PRC1 and kinesin-4. Cell 2013 Jul 18; 154(2):377-90.

  13. 2012
  14. Subramanian R, Kapoor TM. Building complexity: insights into self-organized assembly of microtubule-based architectures. Dev. Cell 2012 Nov 13; 23(5):874-85.

  15. 2010
  16. Subramanian R, Wilson-Kubalek EM, Arthur CP, Bick MJ, Campbell EA, Darst SA, Milligan RA, Kapoor TM. Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein. Cell 2010 Aug 6; 142(3):433-43.

  17. 2009
  18. Subramanian R, Kapoor T. Meiotic spindle self-organization: one plus one equals only one. Curr. Biol. 2009 Apr 14; 19(7):R290-2.

  19. 2007
  20. Subramanian R, Gelles J. Two distinct modes of processive kinesin movement in mixtures of ATP and AMP-PNP. J. Gen. Physiol. 2007 Nov; 130(5):445-55.

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