Center for Computational & Integrative Biology, Massachusetts General Hospital
Department of Molecular Biology, Massachusetts General Hospital
Department of Genetics, Harvard Medical School
Howard Hughes Medical Institute

  Jack W. Szostak
Investigator, Howard Hughes Medical Institute
Professor, Department of Genetics, Harvard Medical School
Alex. A. Rich Distinguished Investigator, Department of Molecular Biology, Massachusetts General Hospital

szostak@molbio.mgh.harvard.edu

  Katarzyna Adamala - Graduate Student
MSc., Organic Synthesis, University of Warsaw

Research: Prebiotic synthesis of lipid and nucleotide derivatives.
  J. Craig Blain - Graduate Student, BBS Program
B.Sc.H., Biochemistry, Queen's University, Kingston, Canada

Research: Synthesis of non-natural nucleic acids; Darwinian evolution in artificial chemical systems

jcblain@fas.harvard.edu
  Itay Budin - Graduate Student, MCB Program
B.S., Biological Engineering, Cornell University

Research: Evolutionary biophysics

ibudin@fas.harvard.edu
  Aaron Engelhart - Post-doc
Ph.D., Georgia Institute of Technology

Research: Self-assembly, nucleic acid polymerization

engelhart@molbio.mgh.harvard.edu
  Christian Hentrich - Post-doc
Ph.D., EMBL and University of Heidelberg, Germany

Research: Protocells, self-organization and microscopy

hentrich@molbio.mgh.harvard.edu
  Ben Heuberger - Post-doc
Ph.D., UC Riverside

Research: In vitro RNA selection, synthetic chemistry, and nonenzymatic informational transfer.

heuberger@molbio.mgh.harvard.edu
  Satoru Horiya - Visiting fellow
B.A. & M.Ed., Tokyo Gakugei University; Ph.D., The Jikei University School of Medicine, Tokyo

Research: Selection of an HIV-related peptide using mRNA display.

shoriya@brandeis.edu
  Matthew Powner - Post-doc
Ph.D., Organic Chemistry, University of Manchester, UK

Research: Organic chemistry, predisposed chemistry, aqueous reactivity, the link between simple abiotic processes and biological structure and function.

powner@molbio.mgh.harvard.edu
  Alonso Ricardo - Post-doc
Ph.D., University of Florida
Bioorganic molecules in the cosmos and the origin of Darwinian molecular systems with Steven Benner

Research: mRNA display as a tool for the discovery of new antibiotics, bioorganic chemistry and to study the origins of life

aricardo@molbio.mgh.harvard.edu
  Yollete V. Guillen Schlippe - Post-doc
Ph.D. Biochemistry, Brandeis University
Enzymology of IMPDH (inosine 5'monophosphate dehydrogenase) with Liz Hedstrom

Research: Ribosomal synthesis of highly modified peptides-reassigniment of codons to expand the genetic code

guillen@molbio.mgh.harvard.edu
  Pam Svec - HHMI Lab Manager


svec@frodo.mgh.harvard.edu
  Isabel Vogt - Undergraduate Student
A.B., Chemical and Physical Biology (expected), Harvard University

Research: Nucleic acid modifications and nonenzymatic polymerization, ribozyme selection

ivogt@college.harvard.edu
  Na Zhang - Post-doc
Ph.D., Cornell U. Medical School
NMR Structural Determination of Guanine-Rich Oligonucleotides and DNA Adducts with Dinshaw Patel

Research: Unnatural nucleic acid folding structure and fatty acid permeabilty using NMR

Na.Zhang@molbio.mgh.harvard.edu
  Shenglong Zhang - Post-doc
Ph.D., Columbia University

Research: Design and synthesis of self-replicating nucleotides for enzyme-free primer extension reaction with the aim of constructing a replicating model protocell capable of spontaneous Darwinian evolution.

slzhang@molbio.mgh.harvard.edu

General Contact Information:

CCIB 7215
Simches Research Center
185 Cambridge Street
Boston, Massachusetts 02114

FAX: 617-643-3328
Lab Manager Phone: 617-726-5102

 

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